Crystallin
From Proteopedia
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'''Crystallin''' is found in the lens of the eye accounting for the transparency and probably increasing the refractive index of it. '''α-, β-, γ-, δ-crystallin''' are named according to the order they are eluted by gel filtration.''' δ-crystallin''' is found in avian and reptilian lenses.<ref>PMID:12729747</ref> | '''Crystallin''' is found in the lens of the eye accounting for the transparency and probably increasing the refractive index of it. '''α-, β-, γ-, δ-crystallin''' are named according to the order they are eluted by gel filtration.''' δ-crystallin''' is found in avian and reptilian lenses.<ref>PMID:12729747</ref> | ||
| - | See [[Alpha crystallin]]. | + | *'''Alpha crystallin''' has chaperone-like properties like the ability to prevent precipitation of denatured proteins<ref>PMID:15575808</ref>. See [[Alpha crystallin]]. |
== Disease == | == Disease == | ||
Revision as of 08:15, 9 June 2024
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References
- ↑ Basak A, Bateman O, Slingsby C, Pande A, Asherie N, Ogun O, Benedek GB, Pande J. High-resolution X-ray crystal structures of human gammaD crystallin (1.25 A) and the R58H mutant (1.15 A) associated with aculeiform cataract. J Mol Biol. 2003 May 16;328(5):1137-47. PMID:12729747
- ↑ Augusteyn RC. alpha-crystallin: a review of its structure and function. Clin Exp Optom. 2004 Nov;87(6):356-66. doi: 10.1111/j.1444-0938.2004.tb03095.x. PMID:15575808 doi:http://dx.doi.org/10.1111/j.1444-0938.2004.tb03095.x
- ↑ Horwitz J. Alpha-crystallin. Exp Eye Res. 2003 Feb;76(2):145-53. doi: 10.1016/s0014-4835(02)00278-6. PMID:12565801 doi:http://dx.doi.org/10.1016/s0014-4835(02)00278-6
- ↑ Pande A, Pande J, Asherie N, Lomakin A, Ogun O, King J, Benedek GB. Crystal cataracts: human genetic cataract caused by protein crystallization. Proc Natl Acad Sci U S A. 2001 May 22;98(11):6116-20. PMID:11371638 doi:http://dx.doi.org/10.1073/pnas.101124798
