Dedicator of cytokinesis protein
From Proteopedia
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== Function == | == Function == | ||
| - | Dedicator of cytokinesis proteins (DOCK) are guanine-nucleotide exchange factors for Rho-family GTPase. DOCKs are required in cell motility and phagocytosis. | + | '''Dedicator of cytokinesis proteins''' (DOCK) are guanine-nucleotide exchange factors for Rho-family GTPase. DOCKs are required in cell motility and phagocytosis. |
== Disease == | == Disease == | ||
Revision as of 10:25, 11 June 2024
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References
- ↑ Su HC. Dedicator of cytokinesis 8 (DOCK8) deficiency. Curr Opin Allergy Clin Immunol. 2010 Dec;10(6):515-20. doi:, 10.1097/ACI.0b013e32833fd718. PMID:20864884 doi:http://dx.doi.org/10.1097/ACI.0b013e32833fd718
- ↑ Yang J, Zhang Z, Roe SM, Marshall CJ, Barford D. Activation of Rho GTPases by DOCK exchange factors is mediated by a nucleotide sensor. Science. 2009 Sep 11;325(5946):1398-402. PMID:19745154 doi:325/5946/1398
