8e3q

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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[8e3q]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8E3Q OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8E3Q FirstGlance]. <br>
<table><tr><td colspan='2'>[[8e3q]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8E3Q OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8E3Q FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 2.68&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8e3q FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8e3q OCA], [https://pdbe.org/8e3q PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8e3q RCSB], [https://www.ebi.ac.uk/pdbsum/8e3q PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8e3q ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8e3q FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8e3q OCA], [https://pdbe.org/8e3q PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8e3q RCSB], [https://www.ebi.ac.uk/pdbsum/8e3q PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8e3q ProSAT]</span></td></tr>
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</table>
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== Function ==
 
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[https://www.uniprot.org/uniprot/CPSF1_HUMAN CPSF1_HUMAN] Component of the cleavage and polyadenylation specificity factor (CPSF) complex that plays a key role in pre-mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A) polymerase and other factors to bring about cleavage and poly(A) addition. This subunit is involved in the RNA recognition step of the polyadenylation reaction.<ref>PMID:14749727</ref>
 
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== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==

Current revision

CRYO-EM STRUCTURE OF the human MPSF

PDB ID 8e3q

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