8r3g
From Proteopedia
(Difference between revisions)
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- | '''Unreleased structure''' | ||
- | + | ==Central glycolytic genes regulator (CggR) bound to DNA operator== | |
- | + | <StructureSection load='8r3g' size='340' side='right'caption='[[8r3g]], [[Resolution|resolution]] 4.40Å' scene=''> | |
- | + | == Structural highlights == | |
- | + | <table><tr><td colspan='2'>[[8r3g]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_subtilis Bacillus subtilis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8R3G OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8R3G FirstGlance]. <br> | |
- | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 4.4Å</td></tr> | |
- | [[Category: | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr> |
+ | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8r3g FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8r3g OCA], [https://pdbe.org/8r3g PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8r3g RCSB], [https://www.ebi.ac.uk/pdbsum/8r3g PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8r3g ProSAT]</span></td></tr> | ||
+ | </table> | ||
+ | == Function == | ||
+ | [https://www.uniprot.org/uniprot/CGGR_BACSU CGGR_BACSU] In the absence of glucose, represses the transcription of the gapA operon, which encodes five key glycolytic enzymes. Binds specifically to the cggR-gapA promoter region and blocks the progression of the RNA polymerase, leading to the arrest of the transcription.<ref>PMID:10799476</ref> <ref>PMID:12622823</ref> <ref>PMID:20462860</ref> | ||
+ | == References == | ||
+ | <references/> | ||
+ | __TOC__ | ||
+ | </StructureSection> | ||
+ | [[Category: Bacillus subtilis]] | ||
+ | [[Category: Large Structures]] | ||
+ | [[Category: Rezacova P]] | ||
+ | [[Category: Skerlova J]] | ||
+ | [[Category: Skubnik K]] | ||
+ | [[Category: Soltysova M]] |
Current revision
Central glycolytic genes regulator (CggR) bound to DNA operator
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