6zv2

<table><tr><td colspan='2'>[[6zv2]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6ZV2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6ZV2 FirstGlance]. <br>

</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6zv2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6zv2 OCA], [https://pdbe.org/6zv2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6zv2 RCSB], [https://www.ebi.ac.uk/pdbsum/6zv2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6zv2 ProSAT]</span></td></tr>

== Function ==

[https://www.uniprot.org/uniprot/PP1RA_HUMAN PP1RA_HUMAN] Scaffold protein which mediates the formation of the PTW/PP1 phosphatase complex by providing a binding platform to each component of the complex. The PTW/PP1 phosphatase complex plays a role in the control of chromatin structure and cell cycle progression during the transition from mitosis into interphase. Mediates interaction of WDR82 and PPP1CA. Inhibitor of PPP1CA and PPP1CC phosphatase activities. Has inhibitory activity on PPP1CA only when phosphorylated. Binds to mRNA, single-stranded DNA (ssDNA), poly(A) and poly(G) homopolymers (By similarity).<ref>PMID:9450550</ref>

<div style="background-color:#fffaf0;">

== Publication Abstract from PubMed ==

[Figure: see text].

A ubiquitous disordered protein interaction module orchestrates transcription elongation.,Cermakova K, Demeulemeester J, Lux V, Nedomova M, Goldman SR, Smith EA, Srb P, Hexnerova R, Fabry M, Madlikova M, Horejsi M, De Rijck J, Debyser Z, Adelman K, Hodges HC, Veverka V Science. 2021 Nov 26;374(6571):1113-1121. doi: 10.1126/science.abe2913. Epub 2021, Nov 25. PMID:34822292<ref>PMID:34822292</ref>

From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>

</div>

<div class="pdbe-citations 6zv2" style="background-color:#fffaf0;"></div>

== References ==

<references/>

[[Category: Homo sapiens]]