Exportin
From Proteopedia
(Difference between revisions)
| Line 5: | Line 5: | ||
*'''XPO-4''' mediates nuclear transport of eukaryotic translation initiation factor 5A<ref>PMID:10944119</ref>.<br /> | *'''XPO-4''' mediates nuclear transport of eukaryotic translation initiation factor 5A<ref>PMID:10944119</ref>.<br /> | ||
*'''XPO-5''' mediates nuclear transport of pre-miroRNAs and short hairpin RNAs<ref>PMID:14681208</ref>.<br /> | *'''XPO-5''' mediates nuclear transport of pre-miroRNAs and short hairpin RNAs<ref>PMID:14681208</ref>.<br /> | ||
| - | *'''XPO- | + | *'''XPO-t''' or '''karyopherin''' is a nuclear transport receptor involved in the export of tRNA to the cytoplasm<ref>PMID:22944664</ref>.<br /> |
==Structural highlights == | ==Structural highlights == | ||
Current revision
| |||||||||||
References
- ↑ Caillot M, Miloudi H, Taly A, Profitós-Pelejà N, Santos JC, Ribeiro ML, Maitre E, Saule S, Roué G, Jardin F, Sola B. Exportin 1-mediated nuclear/cytoplasmic trafficking controls drug sensitivity of classical Hodgkin's lymphoma. Mol Oncol. 2023 Dec;17(12):2546-2564. PMID:36727672 doi:10.1002/1878-0261.13386
- ↑ Lipowsky G, Bischoff FR, Schwarzmaier P, Kraft R, Kostka S, Hartmann E, Kutay U, Gorlich D. Exportin 4: a mediator of a novel nuclear export pathway in higher eukaryotes. EMBO J. 2000 Aug 15;19(16):4362-71. PMID:10944119 doi:http://dx.doi.org/10.1093/emboj/19.16.4362
- ↑ Yi R, Qin Y, Macara IG, Cullen BR. Exportin-5 mediates the nuclear export of pre-microRNAs and short hairpin RNAs. Genes Dev. 2003 Dec 15;17(24):3011-6. Epub 2003 Dec 17. PMID:14681208 doi:http://dx.doi.org/10.1101/gad.1158803
- ↑ Leisegang MS, Martin R, Ramírez AS, Bohnsack MT. Exportin t and Exportin 5: tRNA and miRNA biogenesis Biol Chem. 2012 Jul;393(7):599-604. PMID:22944664 doi:10.1515/hsz-2012-0146
- ↑ Cook AG, Fukuhara N, Jinek M, Conti E. Structures of the tRNA export factor in the nuclear and cytosolic states. Nature. 2009 Sep 3;461(7260):60-5. PMID:19680239 doi:10.1038/nature08394
