Fatty acid-binding protein
From Proteopedia
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<StructureSection load='1fe3' size='350' side='right' scene='48/487562/Cv/4' caption='Human brain-type fatty acid-binding protein complex with oleate (PDB code [[1fe3]]) '> | <StructureSection load='1fe3' size='350' side='right' scene='48/487562/Cv/4' caption='Human brain-type fatty acid-binding protein complex with oleate (PDB code [[1fe3]]) '> | ||
| - | '''Fatty acid-binding protein''' (FABP) are carrier proteins for fatty acids and other lipophilic substances. They facilitate the transfer of fatty acids between extra- and intracellular membranes. FABS coordinate lipid trafficking and signaling in cells<ref>PMID:16424607</ref>. Various FABS differ in their tissue expression. | + | '''Fatty acid-binding protein''' (FABP) are carrier proteins for fatty acids and other lipophilic substances. They facilitate the transfer of fatty acids between extra- and intracellular membranes. FABS coordinate lipid trafficking and signaling in cells<ref>PMID:16424607</ref>. Various FABS differ in their tissue expression. |
| + | *'''IFABP''' is intestinal; | ||
| + | *'''HFABP''' is heart-type; | ||
| + | *'''BFABP''' is brain-type; | ||
| + | *'''LFABP''' is liver-type; | ||
| + | *'''AFABP''' is adipocyte; | ||
| + | *'''LMDABP''' is from flight muscle; | ||
| + | *'''TFABP''' is from testis. | ||
== Relevance == | == Relevance == | ||
Current revision
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References
- ↑ Chmurzynska A. The multigene family of fatty acid-binding proteins (FABPs): function, structure and polymorphism. J Appl Genet. 2006;47(1):39-48. PMID:16424607 doi:http://dx.doi.org/10.1007/BF03194597
- ↑ Balendiran GK, Schnutgen F, Scapin G, Borchers T, Xhong N, Lim K, Godbout R, Spener F, Sacchettini JC. Crystal structure and thermodynamic analysis of human brain fatty acid-binding protein. J Biol Chem. 2000 Sep 1;275(35):27045-54. PMID:10854433 doi:10.1074/jbc.M003001200
