Ferric hydroxamate uptake receptor
From Proteopedia
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== Function == | == Function == | ||
| - | '''Ferric hydroxamate uptake receptor''' or '''ferrichrome-binding periplasmic protein''' proteins FhuA, FhuB, FhuC and FhuD are involved in the uptake of the hydroxamate ferrichrome siderophore for use as an iron source<ref>PMID:17600077</ref>. For more details see [[FhuD]]. | + | '''Ferric hydroxamate uptake receptor''' or '''ferrichrome-binding periplasmic protein''' proteins FhuA, FhuB, FhuC and FhuD are involved in the uptake of the hydroxamate ferrichrome siderophore for use as an iron source<ref>PMID:17600077</ref>. |
| + | *'''FhuA''' is the outer membrane transporter of ferrichrome and is the'' E. coli'' receptor of some phages and colicin M<ref>PMID:9782377</ref>. | ||
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| + | For more details see [[FhuD]]. | ||
== Disease == | == Disease == | ||
''Haemophilus parasuis'' uses Fhu to capture iron and is the cause of the Glasser disease in pigs. | ''Haemophilus parasuis'' uses Fhu to capture iron and is the cause of the Glasser disease in pigs. | ||
Revision as of 05:59, 23 June 2024
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3D structures of Ferric hydroxamate uptake receptor
Updated on 23-June-2024
References
- ↑ Forman S, Nagiec MJ, Abney J, Perry RD, Fetherston JD. Analysis of the aerobactin and ferric hydroxamate uptake systems of Yersinia pestis. Microbiology. 2007 Jul;153(Pt 7):2332-41. PMID:17600077 doi:http://dx.doi.org/10.1099/mic.0.2006/004275-0
- ↑ Bonhivers M, Plançon L, Ghazi A, Boulanger P, le Maire M, Lambert O, Rigaud JL, Letellier L. FhuA, an Escherichia coli outer membrane protein with a dual function of transporter and channel which mediates the transport of phage DNA. Biochimie. 1998 May-Jun;80(5-6):363-9. PMID:9782377 doi:10.1016/s0300-9084(00)80004-8
- ↑ Locher KP, Rees B, Koebnik R, Mitschler A, Moulinier L, Rosenbusch JP, Moras D. Transmembrane signaling across the ligand-gated FhuA receptor: crystal structures of free and ferrichrome-bound states reveal allosteric changes. Cell. 1998 Dec 11;95(6):771-8. PMID:9865695
