Glutathione S-transferase

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*'''pi glutathione S-transferase''' has a orle in carcinogenic processes<ref>PMID:9679544</ref>.
*'''pi glutathione S-transferase''' has a orle in carcinogenic processes<ref>PMID:9679544</ref>.
*'''rho glutathione S-transferase''' detoxifies water from the pollutant dichloroacetate<ref>PMID:25685659</ref>.
*'''rho glutathione S-transferase''' detoxifies water from the pollutant dichloroacetate<ref>PMID:25685659</ref>.
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*'''sigma glutathione S-transferase''' is a detoxifying agent providing drug resistance and acting as vaccine antigen<ref>PMID:38668546</ref>.
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==Relevance==
==Relevance==

Revision as of 07:49, 26 June 2024

Glutathione S-tansferase complex with glutathione (PDB entry 1fhe)

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References

  1. ↑ Oakley A. Glutathione transferases: a structural perspective. Drug Metab Rev. 2011 May;43(2):138-51. doi: 10.3109/03602532.2011.558093. Epub, 2011 Mar 23. PMID:21428697 doi:http://dx.doi.org/10.3109/03602532.2011.558093
  2. ↑ Wongsantichon J, Robinson RC, Ketterman AJ. Epsilon glutathione transferases possess a unique class-conserved subunit interface motif that directly interacts with glutathione in the active site. Biosci Rep. 2015 Oct 20;35(6). pii: e00272. doi: 10.1042/BSR20150183. PMID:26487708 doi:http://dx.doi.org/10.1042/BSR20150183
  3. ↑ Morel F, Aninat C. The glutathione transferase kappa family. Drug Metab Rev. 2011 May;43(2):281-91. PMID:21428694 doi:10.3109/03602532.2011.556122
  4. ↑ Nazar-Stewart V, Motulsky AG, Eaton DL, White E, Hornung SK, Leng ZT, Stapleton P, Weiss NS. The glutathione S-transferase mu polymorphism as a marker for susceptibility to lung carcinoma. Cancer Res. 1993 May 15;53(10 Suppl):2313-8 PMID:8485718
  5. ↑ Kontur WS, Bingman CA, Olmsted CN, Wassarman DR, Ulbrich A, Gall DL, Smith RW, Yusko LM, Fox BG, Noguera DR, Coon JJ, Donohue TJ. Novosphingobium aromaticivorans uses a Nu-class glutathione-S-transferase as a glutathione lyase in breaking the beta-aryl ether bond of lignin. J Biol Chem. 2018 Feb 15. pii: RA117.001268. doi: 10.1074/jbc.RA117.001268. PMID:29449375 doi:http://dx.doi.org/10.1074/jbc.RA117.001268
  6. ↑ Henderson CJ, McLaren AW, Moffat GJ, Bacon EJ, Wolf CR. Pi-class glutathione S-transferase: regulation and function. Chem Biol Interact. 1998 Apr 24;111-112:69-82. PMID:9679544 doi:10.1016/s0009-2797(97)00176-2
  7. ↑ Pandey T, Chhetri G, Chinta R, Kumar B, Singh DB, Tripathi T, Singh AK. Functional classification and biochemical characterization of a novel rho class glutathione S-transferase in Synechocystis PCC 6803. FEBS Open Bio. 2014 Nov 24;5:1-7. PMID:25685659 doi:10.1016/j.fob.2014.11.006
  8. ↑ Sánchez Pérez LC, Zubillaga RA, García-Gutiérrez P, Landa A. Sigma-Class Glutathione Transferases (GSTσ): A New Target with Potential for Helminth Control. Trop Med Infect Dis. 2024 Apr 16;9(4):85. PMID:38668546 doi:10.3390/tropicalmed9040085
  9. ↑ Rossjohn J, Feil SC, Wilce MC, Sexton JL, Spithill TW, Parker MW. Crystallization, structural determination and analysis of a novel parasite vaccine candidate: Fasciola hepatica glutathione S-transferase. J Mol Biol. 1997 Nov 7;273(4):857-72. PMID:9367777 doi:10.1006/jmbi.1997.1338

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