8xir
From Proteopedia
(Difference between revisions)
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- | '''Unreleased structure''' | ||
- | + | ==Structure of pasireotide-SSTR3 G protein complex== | |
- | + | <StructureSection load='8xir' size='340' side='right'caption='[[8xir]], [[Resolution|resolution]] 2.52Å' scene=''> | |
- | + | == Structural highlights == | |
- | + | <table><tr><td colspan='2'>[[8xir]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens], [https://en.wikipedia.org/wiki/Lama_glama Lama glama] and [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8XIR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8XIR FirstGlance]. <br> | |
- | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 2.52Å</td></tr> | |
- | [[Category: | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=004:(2S)-AMINO(PHENYL)ETHANOIC+ACID'>004</scene>, <scene name='pdbligand=A1D5E:(2~{S},4~{R})-4-(2-azanylethylcarbamoyloxy)pyrrolidine-2-carboxylic+acid'>A1D5E</scene>, <scene name='pdbligand=DTR:D-TRYPTOPHAN'>DTR</scene>, <scene name='pdbligand=TY5:O-BENZYL-L-TYROSINE'>TY5</scene></td></tr> |
+ | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8xir FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8xir OCA], [https://pdbe.org/8xir PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8xir RCSB], [https://www.ebi.ac.uk/pdbsum/8xir PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8xir ProSAT]</span></td></tr> | ||
+ | </table> | ||
+ | == Function == | ||
+ | [https://www.uniprot.org/uniprot/SSR3_HUMAN SSR3_HUMAN] Receptor for somatostatin-14 and -28. This receptor is coupled via pertussis toxin sensitive G proteins to inhibition of adenylyl cyclase.<ref>PMID:1337145</ref> | ||
+ | == References == | ||
+ | <references/> | ||
+ | __TOC__ | ||
+ | </StructureSection> | ||
+ | [[Category: Homo sapiens]] | ||
+ | [[Category: Lama glama]] | ||
+ | [[Category: Large Structures]] | ||
+ | [[Category: Synthetic construct]] | ||
+ | [[Category: Wang Y]] | ||
+ | [[Category: Xu HE]] | ||
+ | [[Category: Xu Y]] | ||
+ | [[Category: Zhuang Y]] |
Current revision
Structure of pasireotide-SSTR3 G protein complex
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Categories: Homo sapiens | Lama glama | Large Structures | Synthetic construct | Wang Y | Xu HE | Xu Y | Zhuang Y