1sui

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[[Image:1sui.gif|left|200px]]
[[Image:1sui.gif|left|200px]]
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{{Structure
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<!--
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|PDB= 1sui |SIZE=350|CAPTION= <scene name='initialview01'>1sui</scene>, resolution 2.70&Aring;
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The line below this paragraph, containing "STRUCTURE_1sui", creates the "Structure Box" on the page.
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|SITE=
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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|LIGAND= <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=FRE:FERULOYL+COENZYME+A'>FRE</scene>, <scene name='pdbligand=SAH:S-ADENOSYL-L-HOMOCYSTEINE'>SAH</scene>
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Caffeoyl-CoA_O-methyltransferase Caffeoyl-CoA O-methyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.1.1.104 2.1.1.104] </span>
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or leave the SCENE parameter empty for the default display.
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|GENE= CCOMT ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=3879 Medicago sativa])
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-->
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|DOMAIN=
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{{STRUCTURE_1sui| PDB=1sui | SCENE= }}
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|RELATEDENTRY=[[1sus|1SUS]]
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1sui FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1sui OCA], [http://www.ebi.ac.uk/pdbsum/1sui PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1sui RCSB]</span>
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}}
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'''Alfalfa caffeoyl coenzyme A 3-O-methyltransferase'''
'''Alfalfa caffeoyl coenzyme A 3-O-methyltransferase'''
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[[Category: Noel, J P.]]
[[Category: Noel, J P.]]
[[Category: Zubieta, C.]]
[[Category: Zubieta, C.]]
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[[Category: protein-cofactor-substrate complex]]
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[[Category: Protein-cofactor-substrate complex]]
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[[Category: rossmann fold]]
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[[Category: Rossmann fold]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 09:08:52 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Mar 30 23:47:06 2008''
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Revision as of 06:08, 3 May 2008

Image:1sui.gif

Template:STRUCTURE 1sui

Alfalfa caffeoyl coenzyme A 3-O-methyltransferase


Overview

Caffeoyl coenzyme A 3-O-methyltransferases (CCoAOMTs) are S-adenosyl-l-methionine-dependent O-methyltransferases (OMTs) involved in lignin biosynthesis. Plant CCoAOMTs belong to a distinct family of OMTs, more closely related to the mammalian catechol OMTs than to other plant OMTs. The crystal structure of alfalfa (Medicago sativa) CCoAOMT in complex with the reaction products S-adenosine-l-homocysteine and feruloyl/sinapoyl CoAs presented here belong to a structurally and mechanistically distinct family of plant small molecule OMTs. These structures provide a new understanding of the substrate preferences and the catalytic mechanism accompanying CCoAOMT-mediated O-methylation of CoA-linked phenylpropanoid substrates.

About this Structure

1SUI is a Single protein structure of sequence from Medicago sativa. Full crystallographic information is available from OCA.

Reference

Crystal structures of alfalfa caffeoyl coenzyme A 3-O-methyltransferase., Ferrer JL, Zubieta C, Dixon RA, Noel JP, Plant Physiol. 2005 Mar;137(3):1009-17. Epub 2005 Feb 25. PMID:15734921 Page seeded by OCA on Sat May 3 09:08:52 2008

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