This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


1svc

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 1: Line 1:
[[Image:1svc.gif|left|200px]]
[[Image:1svc.gif|left|200px]]
-
{{Structure
+
<!--
-
|PDB= 1svc |SIZE=350|CAPTION= <scene name='initialview01'>1svc</scene>, resolution 2.600&Aring;
+
The line below this paragraph, containing "STRUCTURE_1svc", creates the "Structure Box" on the page.
-
|SITE=
+
You may change the PDB parameter (which sets the PDB file loaded into the applet)
-
|LIGAND= <scene name='pdbligand=DA:2&#39;-DEOXYADENOSINE-5&#39;-MONOPHOSPHATE'>DA</scene>, <scene name='pdbligand=DC:2&#39;-DEOXYCYTIDINE-5&#39;-MONOPHOSPHATE'>DC</scene>, <scene name='pdbligand=DG:2&#39;-DEOXYGUANOSINE-5&#39;-MONOPHOSPHATE'>DG</scene>, <scene name='pdbligand=DT:THYMIDINE-5&#39;-MONOPHOSPHATE'>DT</scene>
+
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-
|ACTIVITY=
+
or leave the SCENE parameter empty for the default display.
-
|GENE=
+
-->
-
|DOMAIN=
+
{{STRUCTURE_1svc| PDB=1svc | SCENE= }}
-
|RELATEDENTRY=
+
-
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1svc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1svc OCA], [http://www.ebi.ac.uk/pdbsum/1svc PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1svc RCSB]</span>
+
-
}}
+
'''NFKB P50 HOMODIMER BOUND TO DNA'''
'''NFKB P50 HOMODIMER BOUND TO DNA'''
Line 27: Line 24:
[[Category: Harrison, S C.]]
[[Category: Harrison, S C.]]
[[Category: Mueller, C W.]]
[[Category: Mueller, C W.]]
-
[[Category: activator]]
+
[[Category: Activator]]
-
[[Category: dna]]
+
[[Category: Dna]]
-
[[Category: dna-binding]]
+
[[Category: Dna-binding]]
-
[[Category: nuclear protein]]
+
[[Category: Nuclear protein]]
-
[[Category: phosphorylation]]
+
[[Category: Phosphorylation]]
-
[[Category: repeat]]
+
[[Category: Repeat]]
-
[[Category: transcription regulation]]
+
[[Category: Transcription regulation]]
-
 
+
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 09:10:33 2008''
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Mar 30 23:47:25 2008''
+

Revision as of 06:10, 3 May 2008

Image:1svc.gif

Template:STRUCTURE 1svc

NFKB P50 HOMODIMER BOUND TO DNA


Overview

The structure of a large fragment of the p50 subunit of the human transcription factor NF-kappa B, bound as a homodimer to DNA, reveals that the Rel-homology region has two beta-barrel domains that grip DNA in the major groove. Both domains contact the DNA backbone. The amino-terminal specificity domain contains a recognition loop that interacts with DNA bases; the carboxy-terminal dimerization domain bears the site of I-kappa B interaction. The folds of these domains are related to immunoglobulin-like modules. The amino-terminal domain also resembles the core domain of p53.

About this Structure

1SVC is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

Structure of the NF-kappa B p50 homodimer bound to DNA., Muller CW, Rey FA, Sodeoka M, Verdine GL, Harrison SC, Nature. 1995 Jan 26;373(6512):311-7. PMID:7830764 Page seeded by OCA on Sat May 3 09:10:33 2008

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1svc"
Personal tools