8xq7
From Proteopedia
(Difference between revisions)
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| - | '''Unreleased structure''' | ||
| - | + | ==Structure of the sea urchin spSLC9C1 in state-1 w/ cAMP dimer== | |
| - | + | <StructureSection load='8xq7' size='340' side='right'caption='[[8xq7]], [[Resolution|resolution]] 3.15Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[8xq7]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Strongylocentrotus_purpuratus Strongylocentrotus purpuratus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8XQ7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8XQ7 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.15Å</td></tr> | |
| - | [[Category: | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CMP:ADENOSINE-3,5-CYCLIC-MONOPHOSPHATE'>CMP</scene></td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8xq7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8xq7 OCA], [https://pdbe.org/8xq7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8xq7 RCSB], [https://www.ebi.ac.uk/pdbsum/8xq7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8xq7 ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/SL9C1_STRPU SL9C1_STRPU] Electroneutral sodium:proton antiporter that regulates intracellular pH of sperm along with capacitation and fertility. Activated in response to egg-derived chemoattractants, couples membrane voltage to sodium:proton exchange and transduces membrane hyperpolarization to cytoplasmic alkalization to cAMP signaling and ultimately to sperm motility.<ref>PMID:30022052</ref> <ref>PMID:37880360</ref> <ref>PMID:37880361</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Strongylocentrotus purpuratus]] | ||
| + | [[Category: Qu H]] | ||
| + | [[Category: Zheng X]] | ||
Current revision
Structure of the sea urchin spSLC9C1 in state-1 w/ cAMP dimer
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