1swm

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[[Image:1swm.gif|left|200px]]
[[Image:1swm.gif|left|200px]]
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{{Structure
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|PDB= 1swm |SIZE=350|CAPTION= <scene name='initialview01'>1swm</scene>, resolution 1.8&Aring;
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The line below this paragraph, containing "STRUCTURE_1swm", creates the "Structure Box" on the page.
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|SITE=
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|LIGAND= <scene name='pdbligand=AZI:AZIDE+ION'>AZI</scene>, <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>
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{{STRUCTURE_1swm| PDB=1swm | SCENE= }}
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1swm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1swm OCA], [http://www.ebi.ac.uk/pdbsum/1swm PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1swm RCSB]</span>
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}}
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'''X-RAY CRYSTAL STRUCTURE OF THE FERRIC SPERM WHALE MYOGLOBIN: IMIDAZOLE COMPLEX AT 2.0 ANGSTROMS RESOLUTION'''
'''X-RAY CRYSTAL STRUCTURE OF THE FERRIC SPERM WHALE MYOGLOBIN: IMIDAZOLE COMPLEX AT 2.0 ANGSTROMS RESOLUTION'''
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[[Category: Coda, A.]]
[[Category: Coda, A.]]
[[Category: Rizzi, M.]]
[[Category: Rizzi, M.]]
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[[Category: oxygen transport]]
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[[Category: Oxygen transport]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 09:13:21 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Mar 30 23:47:57 2008''
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Revision as of 06:13, 3 May 2008

Image:1swm.gif

Template:STRUCTURE 1swm

X-RAY CRYSTAL STRUCTURE OF THE FERRIC SPERM WHALE MYOGLOBIN: IMIDAZOLE COMPLEX AT 2.0 ANGSTROMS RESOLUTION


Overview

The X-ray crystal structure of the ferric sperm whale (Physeter catodon) myoglobin:imidazole complex has been refined at 2.0 A resolution, to a final R-factor of 14.8%. The overall conformation of the protein is little affected by binding of the ligand. Imidazole is co-ordinated to the heme iron at the distal site, and forces distinguishable local changes in the surrounding protein residues. His64(E7) swings out of the distal pocket and becomes substantially exposed to the solvent: nevertheless, it stabilizes the exogenous ligand by hydrogen bonding. The side-chains of residues Arg45(CD3) and Asp60(E3) are also affected by imidazole association.

About this Structure

1SWM is a Single protein structure of sequence from Physeter catodon. Full crystallographic information is available from OCA.

Reference

X-ray crystal structure of the ferric sperm whale myoglobin: imidazole complex at 2.0 A resolution., Lionetti C, Guanziroli MG, Frigerio F, Ascenzi P, Bolognesi M, J Mol Biol. 1991 Feb 5;217(3):409-12. PMID:1994031 Page seeded by OCA on Sat May 3 09:13:21 2008

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