8ptt
From Proteopedia
(Difference between revisions)
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| - | '''Unreleased structure''' | ||
| - | + | ==Human NUDT5 in complex with MRK-952== | |
| - | + | <StructureSection load='8ptt' size='340' side='right'caption='[[8ptt]], [[Resolution|resolution]] 2.50Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[8ptt]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8PTT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8PTT FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5Å</td></tr> | |
| - | [[Category: | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=F2V:6-[(5~{R})-7-[3-chloranyl-4-(trifluoromethyl)phenyl]-2,7-diazaspiro[4.4]nonan-2-yl]-7-methyl-purine'>F2V</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8ptt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8ptt OCA], [https://pdbe.org/8ptt PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8ptt RCSB], [https://www.ebi.ac.uk/pdbsum/8ptt PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8ptt ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/NUDT5_HUMAN NUDT5_HUMAN] Hydrolyzes with similar activities ADP-ribose ADP-mannose, ADP-glucose, 8-oxo-GDP and 8-oxo-dGDP. Can also hydrolyze other nucleotide sugars with low activity.<ref>PMID:17052728</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Arrowsmith CH]] | ||
| + | [[Category: Bountra C]] | ||
| + | [[Category: Diaz-Saez L]] | ||
| + | [[Category: Edwards AM]] | ||
| + | [[Category: Feyerherm C]] | ||
| + | [[Category: Fischer C]] | ||
| + | [[Category: Huber KVM]] | ||
| + | [[Category: Koekemoer L]] | ||
| + | [[Category: Schneider S]] | ||
| + | [[Category: Sloman S]] | ||
| + | [[Category: Von Delft F]] | ||
Current revision
Human NUDT5 in complex with MRK-952
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Categories: Homo sapiens | Large Structures | Arrowsmith CH | Bountra C | Diaz-Saez L | Edwards AM | Feyerherm C | Fischer C | Huber KVM | Koekemoer L | Schneider S | Sloman S | Von Delft F
