9iiw
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==A local Cryo-EM structure of Bitter taste receptor TAS2R14== | |
| - | + | <StructureSection load='9iiw' size='340' side='right'caption='[[9iiw]], [[Resolution|resolution]] 3.15Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[9iiw]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9IIW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9IIW FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.15Å</td></tr> | |
| - | [[Category: | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=A1AEI:4-methyl-N-[(2M)-2-(1H-tetrazol-5-yl)phenyl]-6-(trifluoromethyl)pyrimidin-2-amine'>A1AEI</scene></td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9iiw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9iiw OCA], [https://pdbe.org/9iiw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9iiw RCSB], [https://www.ebi.ac.uk/pdbsum/9iiw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9iiw ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/T2R14_HUMAN T2R14_HUMAN] Receptor that may play a role in the perception of bitterness and is gustducin-linked. May play a role in sensing the chemical composition of the gastrointestinal content. The activity of this receptor may stimulate alpha gustducin, mediate PLC-beta-2 activation and lead to the gating of TRPM5 (By similarity). | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Duan J]] | ||
| + | [[Category: Tao L]] | ||
| + | [[Category: Xu EH]] | ||
| + | [[Category: Yuan Q]] | ||
Current revision
A local Cryo-EM structure of Bitter taste receptor TAS2R14
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Categories: Homo sapiens | Large Structures | Duan J | Tao L | Xu EH | Yuan Q
