8b4z
From Proteopedia
(Difference between revisions)
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==Rosellinia necatrix megabirnavirus 1-W779 full capsid== | ==Rosellinia necatrix megabirnavirus 1-W779 full capsid== | ||
| - | < | + | <SX load='8b4z' size='340' side='right' viewer='molstar' caption='[[8b4z]], [[Resolution|resolution]] 3.20Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[8b4z]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Rosellinia_necatrix_megabirnavirus_1/W779 Rosellinia necatrix megabirnavirus 1/W779]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8B4Z OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8B4Z FirstGlance]. <br> | <table><tr><td colspan='2'>[[8b4z]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Rosellinia_necatrix_megabirnavirus_1/W779 Rosellinia necatrix megabirnavirus 1/W779]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8B4Z OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8B4Z FirstGlance]. <br> | ||
| - | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8b4z FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8b4z OCA], [https://pdbe.org/8b4z PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8b4z RCSB], [https://www.ebi.ac.uk/pdbsum/8b4z PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8b4z ProSAT]</span></td></tr> | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.2Å</td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8b4z FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8b4z OCA], [https://pdbe.org/8b4z PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8b4z RCSB], [https://www.ebi.ac.uk/pdbsum/8b4z PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8b4z ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
[https://www.uniprot.org/uniprot/D0FZL0_RMBV1 D0FZL0_RMBV1] | [https://www.uniprot.org/uniprot/D0FZL0_RMBV1 D0FZL0_RMBV1] | ||
| + | <div style="background-color:#fffaf0;"> | ||
| + | == Publication Abstract from PubMed == | ||
| + | Rosellinia necatrix megabirnavirus 1-W779 (RnMBV1) is a non-enveloped icosahedral double-stranded (ds)RNA virus that infects the ascomycete fungus Rosellinia necatrix, a causative agent that induces a lethal plant disease white root rot. Herein, we have first resolved the atomic structure of the RnMBV1 capsid at 3.2 A resolution using cryo-electron microscopy (cryo-EM) single-particle analysis. Compared with other non-enveloped icosahedral dsRNA viruses, the RnMBV1 capsid protein structure exhibits an extra-long C-terminal arm and a surface protrusion domain. In addition, the previously unrecognized crown proteins are identified in a symmetry-expanded cryo-EM model and are present over the 3-fold axes. These exclusive structural features of the RnMBV1 capsid could have been acquired for playing essential roles in transmission and/or particle assembly of the megabirnaviruses. Our findings, therefore, will reinforce the understanding of how the structural and molecular machineries of the megabirnaviruses influence the virulence of the disease-related ascomycete fungus. | ||
| + | |||
| + | Capsid structure of a fungal dsRNA megabirnavirus reveals its previously unidentified surface architecture.,Wang H, Salaipeth L, Miyazaki N, Suzuki N, Okamoto K PLoS Pathog. 2023 Feb 27;19(2):e1011162. doi: 10.1371/journal.ppat.1011162. , eCollection 2023 Feb. PMID:36848381<ref>PMID:36848381</ref> | ||
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| + | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | ||
| + | </div> | ||
| + | <div class="pdbe-citations 8b4z" style="background-color:#fffaf0;"></div> | ||
| + | == References == | ||
| + | <references/> | ||
__TOC__ | __TOC__ | ||
| - | </ | + | </SX> |
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: Rosellinia necatrix megabirnavirus 1/W779]] | [[Category: Rosellinia necatrix megabirnavirus 1/W779]] | ||
Current revision
Rosellinia necatrix megabirnavirus 1-W779 full capsid
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