8c97

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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[8c97]] is a 10 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8C97 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8C97 FirstGlance]. <br>
<table><tr><td colspan='2'>[[8c97]] is a 10 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8C97 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8C97 FirstGlance]. <br>
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</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8c97 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8c97 OCA], [https://pdbe.org/8c97 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8c97 RCSB], [https://www.ebi.ac.uk/pdbsum/8c97 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8c97 ProSAT]</span></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 4.07&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8c97 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8c97 OCA], [https://pdbe.org/8c97 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8c97 RCSB], [https://www.ebi.ac.uk/pdbsum/8c97 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8c97 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[https://www.uniprot.org/uniprot/RL14_ECOLI RL14_ECOLI] This protein binds directly to 23S ribosomal RNA. In the E.coli 70S ribosome (PubMed:12809609) it has been modeled to make two contacts with the 16S rRNA of the 30S subunit, forming part of bridges B5 and B8, connecting the 2 subunits. Although the protein undergoes significant rotation during the transition from an initiation to and EF-G bound state, the bridges remain stable. In the 3.5 A resolved structures (PubMed:16272117) L14 and L19 interact and together make contact with the 16S rRNA in bridges B5 and B8.<ref>PMID:22829778</ref> Can also interact with RsfA, in this case bridge B8 probably cannot form, and the 30S and 50S ribosomal subunits do not associate, which represses translation.<ref>PMID:22829778</ref>
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[https://www.uniprot.org/uniprot/RL32_ECOLI RL32_ECOLI]
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== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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<div class="pdbe-citations 8c97" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 8c97" style="background-color:#fffaf0;"></div>
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==See Also==
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*[[Ribosome 3D structures|Ribosome 3D structures]]
== References ==
== References ==
<references/>
<references/>

Current revision

Cryo-EM captures early ribosome assembly in action

PDB ID 8c97

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