8qy9
From Proteopedia
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8qy9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8qy9 OCA], [https://pdbe.org/8qy9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8qy9 RCSB], [https://www.ebi.ac.uk/pdbsum/8qy9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8qy9 ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8qy9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8qy9 OCA], [https://pdbe.org/8qy9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8qy9 RCSB], [https://www.ebi.ac.uk/pdbsum/8qy9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8qy9 ProSAT]</span></td></tr> | ||
</table> | </table> | ||
| + | == Disease == | ||
| + | [https://www.uniprot.org/uniprot/TNR17_HUMAN TNR17_HUMAN] Note=A chromosomal aberration involving TNFRSF17 is found in a form of T-cell acute lymphoblastic leukemia (T-ALL). Translocation t(4;16)(q26;p13) with IL2. | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/TNR17_HUMAN TNR17_HUMAN] Receptor for TNFSF13B/BLyS/BAFF and TNFSF13/APRIL. Promotes B-cell survival and plays a role in the regulation of humoral immunity. Activates NF-kappa-B and JNK.<ref>PMID:10903733</ref> <ref>PMID:10801128</ref> <ref>PMID:10973284</ref> | ||
| + | == References == | ||
| + | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
Current revision
J22.9-H, fully humanized Fab Fragment based on chimeric J22.9-xi IgG against BCMA
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