8tmv
From Proteopedia
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- | '''Unreleased structure''' | ||
- | + | ==HTLV-1 capsid protein N-terminal domain triclinic crystal form with phosphate ion== | |
- | + | <StructureSection load='8tmv' size='340' side='right'caption='[[8tmv]], [[Resolution|resolution]] 1.73Å' scene=''> | |
- | + | == Structural highlights == | |
- | + | <table><tr><td colspan='2'>[[8tmv]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/HTLV-1_subtype_C HTLV-1 subtype C]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8TMV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8TMV FirstGlance]. <br> | |
- | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.73Å</td></tr> | |
- | [[Category: | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr> |
+ | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8tmv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8tmv OCA], [https://pdbe.org/8tmv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8tmv RCSB], [https://www.ebi.ac.uk/pdbsum/8tmv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8tmv ProSAT]</span></td></tr> | ||
+ | </table> | ||
+ | == Function == | ||
+ | [https://www.uniprot.org/uniprot/U3RC00_9DELA U3RC00_9DELA] Binds strongly to viral nucleic acids and promote their aggregation. Also destabilizes the nucleic acids duplexes via highly structured zinc-binding motifs.[ARBA:ARBA00002374] Forms the spherical core of the virus that encapsulates the genomic RNA-nucleocapsid complex.[ARBA:ARBA00037500] Matrix protein.[ARBA:ARBA00003230] The matrix domain targets Gag, Gag-Pro and Gag-Pro-Pol polyproteins to the plasma membrane via a multipartite membrane binding signal, that includes its myristoylated N-terminus.[ARBA:ARBA00037194] | ||
+ | __TOC__ | ||
+ | </StructureSection> | ||
+ | [[Category: HTLV-1 subtype C]] | ||
+ | [[Category: Large Structures]] | ||
+ | [[Category: Jacques DA]] | ||
+ | [[Category: Li N]] | ||
+ | [[Category: Yu RJ]] |
Current revision
HTLV-1 capsid protein N-terminal domain triclinic crystal form with phosphate ion
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