8xrf
From Proteopedia
(Difference between revisions)
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| - | '''Unreleased structure''' | ||
| - | The | + | ==The crystal structure of AsfvTopII in complex with G-DNA== |
| - | + | <StructureSection load='8xrf' size='340' side='right'caption='[[8xrf]], [[Resolution|resolution]] 2.94Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[8xrf]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/African_swine_fever_virus_BA71V African swine fever virus BA71V]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8XRF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8XRF FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.94Å</td></tr> | |
| - | [[Category: | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8xrf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8xrf OCA], [https://pdbe.org/8xrf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8xrf RCSB], [https://www.ebi.ac.uk/pdbsum/8xrf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8xrf ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/TOP2_ASFB7 TOP2_ASFB7] Type II topoisomerase (PubMed:25463606, PubMed:27060564). Processively relaxes supercoiled DNA (PubMed:27060564). Displays DNA-supercoiling activity only when associated with the viral histone-like protein (PubMed:28381576).<ref>PMID:25463606</ref> <ref>PMID:27060564</ref> <ref>PMID:28381576</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: African swine fever virus BA71V]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Gan JH]] | ||
| + | [[Category: Yang J]] | ||
Current revision
The crystal structure of AsfvTopII in complex with G-DNA
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