Squalene synthase

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Current revision (07:47, 14 August 2024) (edit) (undo)
 
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==3D structures of squalene synthase==
==3D structures of squalene synthase==
[[Squalene synthase 3D structures]]
[[Squalene synthase 3D structures]]
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Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
 
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{{#tree:id=OrganizedByTopic|openlevels=0|
 
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*Squalene synthase
 
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**[[3vj8]], [[3vjb]] – hSQS – human<br />
 
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**[[1ezf]] – hSQS (mutant) <br />
 
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**[[4hd1]] – SQS – ''Alicyclobacillus acidocaldarius'' <br />
 
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*Squalene synthase complexes
 
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**[[3lee]] – hSQS + Mg + bisphosphonate inhibitor<br />
 
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**[[3asx]], [[3q2z]], [[3q30]] – hSQS + Mg + PO4 + inhibitor<br />
 
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**[[3vj9]], [[3vja]] – hSQS + Ni<br />
 
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**[[3vjc]] – hSQS + Mg + PO4 + zaragozic acid<br />
 
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**[[3v66]] – hSQS + PO4 + inhibitor<br />
 
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**[[3wef]] – hSQS + FPP analog<br />
 
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**[[3weg]] – hSQS + Mg + FPP analog<br />
 
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**[[3weh]] – hSQS + Mg + presqualene pyrophosphate<br />
 
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**[[3wei]] – hSQS (mutant) + Mn + presqualene pyrophosphate<br />
 
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**[[3wej]], [[3wek]] – hSQS (mutant) + Mg + presqualene pyrophosphate<br />
 
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**[[3wc9]] – hSQS (mutant) + farnesyl thiopyrophosphate<br />
 
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**[[3wcd]] – hSQS (mutant) + phenoxy thiocyanate derivative<br />
 
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**[[3wcf]], [[3wch]], [[3wci]], [[3wcl]] – hSQS (mutant) + imidazole phosphonate derivative<br />
 
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**[[3wcj]] – hSQS (mutant) + pyrrolidine derivative<br />
 
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**[[3wcm]] – hSQS (mutant) + pyridine derivative<br />
 
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**[[3wsa]], [[3wsb]] – hSQS (mutant) + tuberculosis drug<br />
 
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**[[3wef]], [[3weg]] – hSQS + FPP analog <br />
 
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**[[3weh]] – hSQS + presqualene pyrophosphate <br />
 
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**[[3wei]], [[3wej]], [[3wek]] – hSQS (mutant) + presqualene pyrophosphate <br />
 
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**[[3wca]], [[3wcb]], [[3wcc]], [[3wce]], [[3wcg]] – SQS (mutant) + FPP analog – ''Trypanosoma cruzi''<br />
 
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**[[7wgi]] – AfSQS + PO4 + indole – ''Aspergillus flavus''<br />
 
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**[[7wgh]] – AfSQS (mutant) + POP + PO4 +farnesyl thiopyrophosphate<br />
 
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*Dehydrosqualene synthase (DSQS)
 
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**[[3vjd]], [[2zco]] – SaDSQS – ''Staphylococcus aureus'' <br />
 
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**[[3nri]] – SaDSQS + dehydrosqualene <br />
 
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**[[3npr]], [[3adz]] – SaSQS + presqualene pyrophosphate <br />
 
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**[[3lgz]] – SaSQS (mutant) + presqualene pyrophosphate <br />
 
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**[[3vje]] – SaDSQS (mutant) + zaragozic acid <br />
 
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**[[3ae0]] – SaDSQS + geranylgeranyl + thiopyrophosphate <br />
 
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**[[3w7f]], [[5yis]] – SaDSQS + farnesyl + thiopyrophosphate <br />
 
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**[[3acw]], [[3acx]], [[3acy]], [[3tfv]], [[3tfn]], [[3tfp]], [[4f6v]], [[4f6x]], [[2zcs]], [[2zcq]], [[2zy1]], [[2zcr]], [[4e9z]], [[4e9u]], [[4ea0]], [[4ea1]], [[4ea2]] – SaDSQS + inhibitor<br />
 
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== References ==
== References ==

Current revision

Structure of SQS complex with FPP analog and Mg+2 ions (green) (PDB code 3wca).

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky

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