Syntaxin
From Proteopedia
(Difference between revisions)
| Line 6: | Line 6: | ||
*'''Stx-1''' is essential for the formation of the SNARE complex involved in the fusion machinery in the brain. Stx-1 forms a 4-helical bundle complex with proteins SNAP-25 and VAMP2 which drives fusion of vesicles with the plasma membrane<ref>PMID:26903802</ref>. The coiled-coil bundle structure is formed by the interactions of the complex SNARE motifs<ref>PMID:24218570</ref>. | *'''Stx-1''' is essential for the formation of the SNARE complex involved in the fusion machinery in the brain. Stx-1 forms a 4-helical bundle complex with proteins SNAP-25 and VAMP2 which drives fusion of vesicles with the plasma membrane<ref>PMID:26903802</ref>. The coiled-coil bundle structure is formed by the interactions of the complex SNARE motifs<ref>PMID:24218570</ref>. | ||
*'''Stx-1A''' regulates the function of transmembrane proteins like ion channels and neurotransmitter transporters<ref>PMID:18617632</ref>. | *'''Stx-1A''' regulates the function of transmembrane proteins like ion channels and neurotransmitter transporters<ref>PMID:18617632</ref>. | ||
| + | *'''Stx-6''' is a SNARE protein involved in a variety of internal membrane fusion events. | ||
| + | *'''Stx-7''' is involved in endosomal membrane fusion<ref>PMID:34408265</ref>. | ||
== Relevance == | == Relevance == | ||
Revision as of 06:41, 18 August 2024
| |||||||||||
