Thrombin 3D Structures

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Current revision (08:30, 19 August 2024) (edit) (undo)
 
Line 25: Line 25:
**[[2h9t]] - hThr HC + LC + suramin + PPACK<BR />
**[[2h9t]] - hThr HC + LC + suramin + PPACK<BR />
**[[1z8i]], [[1z8j]] - hThr HC + LC (mutant) + PPACK<BR />
**[[1z8i]], [[1z8j]] - hThr HC + LC (mutant) + PPACK<BR />
-
**[[1b7x]], [[1sfq]], [[1shh]], [[1thp]], [[2thf]], [[4rko]] - hThr HC (mutant) + LC + PPACK<BR />
+
**[[1b7x]], [[1sfq]], [[1shh]], [[1thp]], [[2thf]], [[2pgq]],[[4rko]] - hThr HC (mutant) + LC + PPACK<BR />
**[[1ook]], [[6v64]] - hThr HC + LC + PPACK<BR />
**[[1ook]], [[6v64]] - hThr HC + LC + PPACK<BR />
 +
**[[6gwe]], [[6t7h]] - hThr HC + LC + macrocycle<br />
 +
**[[5cmx]], [[5ew1]], [[5ew2]] - hThr HC + LC + DNA<br />
 +
**[[5do4]] - hThr HC + LC + RNA<br />
**[[2hpp]], [[2hpq]] - hThr HC + LC + PThr residues 214-292 + PPACK<BR />
**[[2hpp]], [[2hpq]] - hThr HC + LC + PThr residues 214-292 + PPACK<BR />
**[[3pma]] – bThr HC + LC residues 336-364 + sucrose octasulfate<br />
**[[3pma]] – bThr HC + LC residues 336-364 + sucrose octasulfate<br />
Line 42: Line 45:
**[[1eoj]], [[1eol]], [[1g37]], [[1nrn]], [[1nro]], [[1nrp]], [[1nrq]], [[1nrr]], [[1nrs]] - hThr HC + peptide inhibitor<br />
**[[1eoj]], [[1eol]], [[1g37]], [[1nrn]], [[1nro]], [[1nrp]], [[1nrq]], [[1nrr]], [[1nrs]] - hThr HC + peptide inhibitor<br />
**[[1hlt]] - hThr HC + LC + thrombomodulin peptide<br />
**[[1hlt]] - hThr HC + LC + thrombomodulin peptide<br />
 +
**[[3qdz]] - hThr HC (mutant) + LC + PAR4 peptide<br />
**[[4ch2]], [[4ch8]] - hThr HC + LC + platelet glycoprotein IB α chain peptide <br />
**[[4ch2]], [[4ch8]] - hThr HC + LC + platelet glycoprotein IB α chain peptide <br />
**[[2ank]], [[3po1]] - hThr HC + LC + peptide + inhibitor<br />
**[[2ank]], [[3po1]] - hThr HC + LC + peptide + inhibitor<br />
Line 82: Line 86:
**[[3pmh]] - hThr HC + LC + platelet glycoprotein IB α chain<br />
**[[3pmh]] - hThr HC + LC + platelet glycoprotein IB α chain<br />
**[[3b23]] - hThr HC + LC + variegin<br />
**[[3b23]] - hThr HC + LC + variegin<br />
 +
**[[1id5]] - hThr HC + LC + ecotin<br />
**[[6tkh]], [[6tki]], [[6tkj]] - hThr HC + LC + tsetse Thr inhibitor<br />
**[[6tkh]], [[6tki]], [[6tkj]] - hThr HC + LC + tsetse Thr inhibitor<br />
**[[5e8e]] - hThr HC + LC + antibody<br />
**[[5e8e]] - hThr HC + LC + antibody<br />
Line 92: Line 97:
*'''Prothrombin'''
*'''Prothrombin'''
-
**[[2afq]], [[3e6p]], [[3u69]], [[6v5t]] - hPThr HC + LC<br />
+
**[[2afq]], [[3u69]] - hPThr HC + LC<br />
**[[3s7h]], [[3s7k]], [[6p9u]] – hPThr HC + LC (mutant) <br />
**[[3s7h]], [[3s7k]], [[6p9u]] – hPThr HC + LC (mutant) <br />
**[[1rd3]], [[1tq0]], [[2gp9]], [[2pgb]], [[3bei]], [[4h6s]], [[4h6t]], [[4hzh]], [[6bjr]], [[6c2w]] - hPThr HC (mutant) + LC<br />
**[[1rd3]], [[1tq0]], [[2gp9]], [[2pgb]], [[3bei]], [[4h6s]], [[4h6t]], [[4hzh]], [[6bjr]], [[6c2w]] - hPThr HC (mutant) + LC<br />
Line 101: Line 106:
**[[6cym]] - hPThr HC + LC + inhibitor<br />
**[[6cym]] - hPThr HC + LC + inhibitor<br />
-
**[[3qdz]] – hPThr HC (mutant) + LC + proteinase-activated receptor 4 peptide<br />
 
**[[3bef]], [[3lu9]] - hPThr HC + LC (mutant) + proteinase-activated receptor 1 peptide<br />
**[[3bef]], [[3lu9]] - hPThr HC + LC (mutant) + proteinase-activated receptor 1 peptide<br />
**[[1sr5]] - hPThr HC + LC + antithrombin III<br />
**[[1sr5]] - hPThr HC + LC + antithrombin III<br />
-
**[[3k65]] - hPThr HC residues 315-622 (mutant) + LC residues 199-314<br />
 
**[[3f68]] - hPThr HC residues 364-622 + LC residues 328-363 + hirudin peptide<br />
**[[3f68]] - hPThr HC residues 364-622 + LC residues 328-363 + hirudin peptide<br />
**[[1jwt]], [[3c1k]] - hPThr HC + inhibitor<br />
**[[1jwt]], [[3c1k]] - hPThr HC + inhibitor<br />
**[[4hfp]] - hPThr HC (mutant) + LC + inhibitor<br />
**[[4hfp]] - hPThr HC (mutant) + LC + inhibitor<br />
-
**[[1tq7]], [[2pgq]] - hPThr HC (mutant) + LC + PPACK<BR />
+
**[[1tq7]] - hPThr HC (mutant) + LC + PPACK<BR />
-
**[[6gwe]], [[6t7h]] - hPThr HC + LC + macrocycle<br />
+
**[[1g30]], [[1g32]], [[1k21]], [[1k22]], [[1o5g]], [[1sb1]], [[1t4u]], [[1t4v]], [[3tu7]], [[4lxb]], [[5jfd]], [[5jzy]], [[5lce]], [[6eo8]], [[6eo9]] [[6fjt]], [[6gbw]], [[6hsx]], [[6i51]], [[6rot]], [[6t3m]], [[6t3q]], [[6t4a]], [[6t52]], [[6t53]], [[6t54]], [[6t55]], [[6t56]], [[6t57]], [[6t89]], [[6t8a]], [[6tdt]], [[6y02]], [[6y9h]], [[6yb6]], [[6yhg]], [[6yhj]], [[6ymp]], [[6yn3]], [[6yqv]], [[6ysj]], [[6ysx]], [[6zug]], [[6zuh]], [[6zun]], [[6zuu]], [[6zuw]], [[6zux]], [[6zv7]], [[6zv8]] - hPThr HC + LC + hirudin peptide + inhibitor<br />
-
**[[1g30]], [[1g32]], [[1k21]], [[1k22]], [[1o5g]], [[1sb1]], [[1t4u]], [[1t4v]], [[2cno]], [[3tu7]], [[4lxb]], [[5jfd]], [[5jzy]], [[5lce]], [[6eo8]], [[6eo9]] [[6fjt]], [[6gbw]], [[6hsx]], [[6i51]], [[6rot]], [[6t3m]], [[6t3q]], [[6t4a]], [[6t52]], [[6t53]], [[6t54]], [[6t55]], [[6t56]], [[6t57]], [[6t89]], [[6t8a]], [[6tdt]], [[6y02]], [[6y9h]], [[6yb6]], [[6yhg]], [[6yhj]], [[6ymp]], [[6yn3]], [[6yqv]], [[6ysj]], [[6ysx]], [[6zug]], [[6zuh]], [[6zun]], [[6zuu]], [[6zuw]], [[6zux]], [[6zv7]], [[6zv8]] - hPThr HC + LC + hirudin peptide + inhibitor<br />
+
**[[4ax9]] - hPThr HC + LC + hirudin peptide<br />
**[[4ax9]] - hPThr HC + LC + hirudin peptide<br />
**[[1twx]] - hPThr HC (mutant) + LC + hirudin peptide<br />
**[[1twx]] - hPThr HC (mutant) + LC + hirudin peptide<br />
**[[2hwl]] - hPThr HC (mutant) + LC + fibrinogen γ’ peptide<br />
**[[2hwl]] - hPThr HC (mutant) + LC + fibrinogen γ’ peptide<br />
-
**[[4dii]], [[4i7y]], [[5ew1]], [[5ew2]], [[5cmx]], [[6eo6]], [[6eo7]], [[6evv]], [[6gn7]], [[6z8v]] - hPThr HC + LC + aptamer<br />
+
**[[4dii]], [[4i7y]], [[6eo6]], [[6eo7]], [[6evv]], [[6gn7]], [[6z8v]] - hPThr HC + LC + DNA aptamer<br />
-
**[[5do4]] - hPThr HC + LC + RNA<br />
+
**[[7a0d]], [[7a0e]], [[7a0f]] - bPThr + hirudin peptide<br />
**[[7a0d]], [[7a0e]], [[7a0f]] - bPThr + hirudin peptide<br />
*Prothrombin complex with protein
*Prothrombin complex with protein
-
**[[1id5]] - hPThr HC + LC + ecotin<br />
 
**[[1p8v]] - hPThr HC + LC + platelet glycoprotein IB α chain<br />
**[[1p8v]] - hPThr HC + LC + platelet glycoprotein IB α chain<br />
**[[3gis]] - hPThr HC residues 364-622 (mutant) + LC residues 315-363 + thrombomodulin<br />
**[[3gis]] - hPThr HC residues 364-622 (mutant) + LC residues 315-363 + thrombomodulin<br />
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**[[6tkg]], [[6tkl]] - hPThr HC + LC + tsetse Thr inhibitor<br />
**[[6tkg]], [[6tkl]] - hPThr HC + LC + tsetse Thr inhibitor<br />
-
*'''Prethrombin-1'''
+
*'''Prethrombin-1 residues 199-622'''
-
**[[3nxp]] - hThr residues 199-622
+
**[[3nxp]] - hThr
-
*'''Prethrombin-2'''
+
*'''Prethrombin-2 residues 328-622'''
 +
**[[6v5t]] – hThr<br />
**[[1nu9]] – hThr + staphylocoagulase<br />
**[[1nu9]] – hThr + staphylocoagulase<br />
**[[1mkw]], [[1mkx]] – hThr + bThr HC + LC<br />
**[[1mkw]], [[1mkx]] – hThr + bThr HC + LC<br />
**[[1hag]], [[1hah]] – hThr + hirudin peptide<br />
**[[1hag]], [[1hah]] – hThr + hirudin peptide<br />
**[[1hai]] – hThr + inhibitor<br />
**[[1hai]] – hThr + inhibitor<br />
-
**[[3sqe]], [[3sqh]] - hThr (mutant)
+
**[[3sqe]], [[3sqh]] - hThr (mutant)<br />
 +
**[[3k65]] - hThr HC residues 315-622 (mutant) + LC residues 199-314<br />
*'''Meizothrombin'''
*'''Meizothrombin'''
-
**[[1a0h]] – bMThr
+
**[[3e6p]] – hMthr HC 364-622 + LC 206-363
 +
**[[1a0h]] – bMThr HC 367-625 + LC 208-366
*'''Saxthrombin'''
*'''Saxthrombin'''
-
**[[3s69]] – Thr – ''Gloydis saxatilis''<br />
+
**[[3s69]] – Thr – Gloydis saxatilis<br />
}}
}}
[[Category:Topic Page]]
[[Category:Topic Page]]

Current revision

3D Structures of thrombin

Updated on 19-August-2024 - For a general description of the protein see Thrombin

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel

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