8tbr

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (05:20, 28 August 2024) (edit) (undo)
 
Line 1: Line 1:
-
'''Unreleased structure'''
 
-
The entry 8tbr is ON HOLD until Paper Publication
+
==Crystal Structure of Dihydrofolate reductase (DHFR) from Mycobacterium ulcerans Agy99 in complex with NADP and inhibitor MAM758==
-
 
+
<StructureSection load='8tbr' size='340' side='right'caption='[[8tbr]], [[Resolution|resolution]] 1.75&Aring;' scene=''>
-
Authors: Seattle Structural Genomics Center for Infectious Disease, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
+
== Structural highlights ==
-
 
+
<table><tr><td colspan='2'>[[8tbr]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_ulcerans_Agy99 Mycobacterium ulcerans Agy99]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8TBR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8TBR FirstGlance]. <br>
-
Description: Crystal Structure of Dihydrofolate reductase (DHFR) from Mycobacterium ulcerans Agy99 in complex with NADP and inhibitor MAM758
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.75&#8491;</td></tr>
-
[[Category: Unreleased Structures]]
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8tbr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8tbr OCA], [https://pdbe.org/8tbr PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8tbr RCSB], [https://www.ebi.ac.uk/pdbsum/8tbr PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8tbr ProSAT]</span></td></tr>
-
[[Category: Seattle Structural Genomics Center For Infectious Disease, Seattle Structural Genomics Center For Infectious Disease (Ssgcid)]]
+
</table>
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/A0PQG8_MYCUA A0PQG8_MYCUA] Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.[PIRNR:PIRNR000194]
 +
__TOC__
 +
</StructureSection>
 +
[[Category: Large Structures]]
 +
[[Category: Mycobacterium ulcerans Agy99]]
 +
[[Category: Structural genomic]]

Current revision

Crystal Structure of Dihydrofolate reductase (DHFR) from Mycobacterium ulcerans Agy99 in complex with NADP and inhibitor MAM758

PDB ID 8tbr

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/8tbr"
Personal tools