1t6s

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{{Structure
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{{STRUCTURE_1t6s| PDB=1t6s | SCENE= }}
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1t6s FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1t6s OCA], [http://www.ebi.ac.uk/pdbsum/1t6s PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1t6s RCSB]</span>
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'''Crystal structure of a conserved hypothetical protein from Chlorobium tepidum'''
'''Crystal structure of a conserved hypothetical protein from Chlorobium tepidum'''
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[[Category: Kim, S H.]]
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[[Category: a winged helix-turn-helix]]
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[[Category: A winged helix-turn-helix]]
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[[Category: berkeley structural genomics center]]
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[[Category: protein structure initiative]]
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Revision as of 06:36, 3 May 2008

Template:STRUCTURE 1t6s

Crystal structure of a conserved hypothetical protein from Chlorobium tepidum


Overview

Structural maintenance of chromosome (SMC) proteins are essential in chromosome condensation and interact with non-SMC proteins in eukaryotes and with segregation and condensation proteins (ScpA and ScpB) in prokaryotes. The highly conserved gene in Chlorobium tepidum gi 21646405 encodes ScpB (ScpB_ChTe). The high resolution crystal structure of ScpB_ChTe shows that the monomeric structure consists of two similarly shaped globular domains composed of three helices sided by beta-strands [a winged helix-turn-helix (HTH)], a motif observed in the C-terminal domain of Scc1, a functionally related eukaryotic ScpA homolog, as well as in many DNA binding proteins.

About this Structure

1T6S is a Single protein structure of sequence from Chlorobium tepidum tls. Full crystallographic information is available from OCA.

Reference

Crystal structure of ScpB from Chlorobium tepidum, a protein involved in chromosome partitioning., Kim JS, Shin DH, Pufan R, Huang C, Yokota H, Kim R, Kim SH, Proteins. 2006 Feb 1;62(2):322-8. PMID:16294331 Page seeded by OCA on Sat May 3 09:36:06 2008

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