8yk7
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Structure of Rib domain from surface adhesin of Limosilactobacillus reuteri== | |
| + | <StructureSection load='8yk7' size='340' side='right'caption='[[8yk7]], [[Resolution|resolution]] 1.35Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[8yk7]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Limosilactobacillus_reuteri Limosilactobacillus reuteri]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8YK7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8YK7 FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.35Å</td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8yk7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8yk7 OCA], [https://pdbe.org/8yk7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8yk7 RCSB], [https://www.ebi.ac.uk/pdbsum/8yk7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8yk7 ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/A0A2T5Q5G6_LIMRT A0A2T5Q5G6_LIMRT] | ||
| + | <div style="background-color:#fffaf0;"> | ||
| + | == Publication Abstract from PubMed == | ||
| + | The immunoglobulin (Ig)-like domain is found in a broad range of proteins with diverse functional roles. While an essential beta-sandwich fold is maintained, considerable structural variations exist and are critical for functional diversity. The Rib-domain family, primarily found as tandem-repeat modules in the surface proteins of Gram-positive bacteria, represents another significant structural variant of the Ig-like fold. However, limited structural and functional exploration of this family has been conducted, which significantly restricts the understanding of its evolution and significance within the Ig superclass. In this work, a high-resolution crystal structure of a Rib domain derived from the probiotic bacterium Limosilactobacillus reuteri is presented. This protein, while sharing significant structural similarity with homologous domains from other bacteria, exhibits a significantly increased thermal resistance. The potential structural features contributing to this stability are discussed. Moreover, the presence of two copper-binding sites, with one positioned on the interface, suggests potential functional roles that warrant further investigation. | ||
| - | + | Crystal structure of the Rib domain of the cell-wall-anchored surface protein from Limosilactobacillus reuteri.,Xue Y, Wu Z, Kang X Acta Crystallogr F Struct Biol Commun. 2024 Sep 1;80(Pt 9):228-233. doi: , 10.1107/S2053230X24007970. Epub 2024 Aug 28. PMID:39196706<ref>PMID:39196706</ref> | |
| - | + | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | |
| - | [[Category: | + | </div> |
| + | <div class="pdbe-citations 8yk7" style="background-color:#fffaf0;"></div> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Limosilactobacillus reuteri]] | ||
| + | [[Category: Kang X]] | ||
| + | [[Category: Xue Y]] | ||
Current revision
Structure of Rib domain from surface adhesin of Limosilactobacillus reuteri
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