9flc

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m (Protected "9flc" [edit=sysop:move=sysop])
Current revision (06:14, 11 September 2024) (edit) (undo)
 
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'''Unreleased structure'''
 
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The entry 9flc is ON HOLD
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==Crystal structure of haspin (GSG2) in complex with MU1668==
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<StructureSection load='9flc' size='340' side='right'caption='[[9flc]], [[Resolution|resolution]] 2.18&Aring;' scene=''>
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Authors: Chaikuad, A., Paruch, K., Knapp, S., Structural Genomics Consortium (SGC)
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== Structural highlights ==
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<table><tr><td colspan='2'>[[9flc]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9FLC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9FLC FirstGlance]. <br>
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Description: Crystal structure of haspin (GSG2) in complex with MU1668
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.18&#8491;</td></tr>
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[[Category: Unreleased Structures]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9flc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9flc OCA], [https://pdbe.org/9flc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9flc RCSB], [https://www.ebi.ac.uk/pdbsum/9flc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9flc ProSAT]</span></td></tr>
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[[Category: Paruch, K]]
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</table>
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[[Category: Chaikuad, A]]
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== Function ==
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[[Category: Structural Genomics Consortium (Sgc)]]
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[https://www.uniprot.org/uniprot/HASP_HUMAN HASP_HUMAN] Serine/threonine-protein kinase that phosphorylates histone H3 at 'Ser-3' (H3T3ph) during mitosis. This positions and activates AURKB and other components of the chromosomal passenger complex (CPC) at centromeres to ensure proper chromatid cohesion, metaphase alignment and normal progression through the cell cycle.<ref>PMID:11228240</ref> <ref>PMID:15681610</ref> <ref>PMID:17084365</ref> <ref>PMID:20705812</ref> <ref>PMID:20929775</ref>
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[[Category: Knapp, S]]
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Homo sapiens]]
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[[Category: Large Structures]]
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[[Category: Chaikuad A]]
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[[Category: Knapp S]]
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[[Category: Paruch K]]

Current revision

Crystal structure of haspin (GSG2) in complex with MU1668

PDB ID 9flc

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