9flq

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m (Protected "9flq" [edit=sysop:move=sysop])
Current revision (06:14, 11 September 2024) (edit) (undo)
 
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'''Unreleased structure'''
 
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The entry 9flq is ON HOLD
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==Crystal structure of human Haspin (GSG2) kinase bound to MU1959==
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<StructureSection load='9flq' size='340' side='right'caption='[[9flq]], [[Resolution|resolution]] 1.85&Aring;' scene=''>
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Authors: Kraemer, A., Paruch, K., Knapp, S., Structural Genomics Consortium (SGC)
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== Structural highlights ==
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<table><tr><td colspan='2'>[[9flq]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9FLQ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9FLQ FirstGlance]. <br>
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Description: Crystal structure of human Haspin (GSG2) kinase bound to MU1959
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.85&#8491;</td></tr>
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[[Category: Unreleased Structures]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9flq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9flq OCA], [https://pdbe.org/9flq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9flq RCSB], [https://www.ebi.ac.uk/pdbsum/9flq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9flq ProSAT]</span></td></tr>
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[[Category: Structural Genomics Consortium (Sgc)]]
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</table>
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[[Category: Knapp, S]]
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== Function ==
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[[Category: Kraemer, A]]
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[https://www.uniprot.org/uniprot/HASP_HUMAN HASP_HUMAN] Serine/threonine-protein kinase that phosphorylates histone H3 at 'Ser-3' (H3T3ph) during mitosis. This positions and activates AURKB and other components of the chromosomal passenger complex (CPC) at centromeres to ensure proper chromatid cohesion, metaphase alignment and normal progression through the cell cycle.<ref>PMID:11228240</ref> <ref>PMID:15681610</ref> <ref>PMID:17084365</ref> <ref>PMID:20705812</ref> <ref>PMID:20929775</ref>
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[[Category: Paruch, K]]
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Homo sapiens]]
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[[Category: Large Structures]]
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[[Category: Knapp S]]
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[[Category: Kraemer A]]
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[[Category: Paruch K]]

Current revision

Crystal structure of human Haspin (GSG2) kinase bound to MU1959

PDB ID 9flq

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