3geu

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Current revision (07:58, 9 October 2024) (edit) (undo)
 
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<StructureSection load='3geu' size='340' side='right'caption='[[3geu]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
<StructureSection load='3geu' size='340' side='right'caption='[[3geu]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3geu]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Staac Staac]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3GEU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3GEU FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3geu]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Staphylococcus_aureus_subsp._aureus_COL Staphylococcus aureus subsp. aureus COL]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3GEU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3GEU FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=FMT:FORMIC+ACID'>FMT</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
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<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=FMT:FORMIC+ACID'>FMT</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">icaR, SACOL2688 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=93062 STAAC])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3geu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3geu OCA], [https://pdbe.org/3geu PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3geu RCSB], [https://www.ebi.ac.uk/pdbsum/3geu PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3geu ProSAT], [https://www.topsan.org/Proteins/CSGID/3geu TOPSAN]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3geu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3geu OCA], [https://pdbe.org/3geu PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3geu RCSB], [https://www.ebi.ac.uk/pdbsum/3geu PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3geu ProSAT], [https://www.topsan.org/Proteins/CSGID/3geu TOPSAN]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[https://www.uniprot.org/uniprot/ICAR_STAAC ICAR_STAAC]] Represses transcription of the icaADBC operon necessary for biofilm production.
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[https://www.uniprot.org/uniprot/ICAR_STAAC ICAR_STAAC] Represses transcription of the icaADBC operon necessary for biofilm production.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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<jmolCheckbox>
<jmolCheckbox>
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ge/3geu_consurf.spt"</scriptWhenChecked>
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ge/3geu_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
</jmolCheckbox>
</jmolCheckbox>
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</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Staac]]
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[[Category: Staphylococcus aureus subsp. aureus COL]]
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[[Category: Anderson, S M]]
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[[Category: Anderson SM]]
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[[Category: Anderson, W F]]
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[[Category: Anderson WF]]
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[[Category: Brunzelle, J S]]
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[[Category: Brunzelle JS]]
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[[Category: Structural genomic]]
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[[Category: Papazisi L]]
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[[Category: Papazisi, L]]
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[[Category: Savchenko A]]
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[[Category: Savchenko, A]]
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[[Category: Skarina T]]
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[[Category: Skarina, T]]
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[[Category: Wawrzak Z]]
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[[Category: Wawrzak, Z]]
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[[Category: Cell adhesion]]
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[[Category: Csgid]]
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[[Category: Dna-binding]]
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[[Category: Idp00851]]
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[[Category: Intercellular adhesion regulator]]
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[[Category: Repressor]]
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[[Category: Tetr family]]
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[[Category: Transcription]]
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[[Category: Transcription regulation]]
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Current revision

Crystal Structure of IcaR from Staphylococcus aureus, a member of the tetracycline repressor protein family

PDB ID 3geu

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