6zve
From Proteopedia
(Difference between revisions)
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6zve FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6zve OCA], [https://pdbe.org/6zve PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6zve RCSB], [https://www.ebi.ac.uk/pdbsum/6zve PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6zve ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6zve FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6zve OCA], [https://pdbe.org/6zve PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6zve RCSB], [https://www.ebi.ac.uk/pdbsum/6zve PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6zve ProSAT]</span></td></tr> | ||
</table> | </table> | ||
| - | == Function == | ||
| - | [https://www.uniprot.org/uniprot/GAB2_HUMAN GAB2_HUMAN] Adapter protein which acts downstream of several membrane receptors including cytokine, antigen, hormone, cell matrix and growth factor receptors to regulate multiple signaling pathways. Regulates osteoclast differentiation mediating the TNFRSF11A/RANK signaling. In allergic response, it plays a role in mast cells activation and degranulation through PI-3-kinase regulation. Also involved in the regulation of cell proliferation and hematopoiesis.<ref>PMID:15750601</ref> <ref>PMID:19172738</ref> | ||
| - | == References == | ||
| - | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
Current revision
14-3-3 Sigma in complex with phosphorylated Gab2pT391 peptide - 1h incubation
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