4baf

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Current revision (06:22, 17 October 2024) (edit) (undo)
 
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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4baf]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4BAF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4BAF FirstGlance]. <br>
<table><tr><td colspan='2'>[[4baf]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4BAF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4BAF FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=EU3:EUROPIUM+(III)+ION'>EU3</scene>, <scene name='pdbligand=IKX:4-(4-(2-HYDROXYETHYL)-1H-1,2,3-TRIAZOL-1-YL)PYRIDINE-2,6-DICARBOXYLIC+ACID'>IKX</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.507&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[3zvq|3zvq]], [[4a7d|4a7d]], [[4a8a|4a8a]], [[4a8b|4a8b]], [[4aga|4aga]], [[4axt|4axt]], [[4b0d|4b0d]], [[4b1a|4b1a]], [[4b49|4b49]], [[4b4e|4b4e]], [[4b4i|4b4i]], [[4b4j|4b4j]], [[4bad|4bad]]</div></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=EU3:EUROPIUM+(III)+ION'>EU3</scene>, <scene name='pdbligand=IKX:4-(4-(2-HYDROXYETHYL)-1H-1,2,3-TRIAZOL-1-YL)PYRIDINE-2,6-DICARBOXYLIC+ACID'>IKX</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Lysozyme Lysozyme], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.17 3.2.1.17] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4baf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4baf OCA], [https://pdbe.org/4baf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4baf RCSB], [https://www.ebi.ac.uk/pdbsum/4baf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4baf ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4baf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4baf OCA], [https://pdbe.org/4baf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4baf RCSB], [https://www.ebi.ac.uk/pdbsum/4baf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4baf ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[https://www.uniprot.org/uniprot/LYSC_CHICK LYSC_CHICK]] Lysozymes have primarily a bacteriolytic function; those in tissues and body fluids are associated with the monocyte-macrophage system and enhance the activity of immunoagents. Has bacteriolytic activity against M.luteus.<ref>PMID:22044478</ref>
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[https://www.uniprot.org/uniprot/LYSC_CHICK LYSC_CHICK] Lysozymes have primarily a bacteriolytic function; those in tissues and body fluids are associated with the monocyte-macrophage system and enhance the activity of immunoagents. Has bacteriolytic activity against M.luteus.<ref>PMID:22044478</ref>
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== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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[[Category: Gallus gallus]]
[[Category: Gallus gallus]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Lysozyme]]
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[[Category: Gautier A]]
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[[Category: Gautier, A]]
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[[Category: Girard E]]
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[[Category: Girard, E]]
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[[Category: Kahn R]]
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[[Category: Kahn, R]]
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[[Category: Nauton L]]
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[[Category: Nauton, L]]
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[[Category: Talon R]]
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[[Category: Talon, R]]
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[[Category: Anomalous scattering]]
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[[Category: Click-chemistry]]
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[[Category: De novo phasing]]
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[[Category: Dipicolinate]]
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[[Category: Hydrolase]]
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[[Category: Lanthanide complex]]
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Current revision

Hen egg-white lysozyme structure in complex with the europium tris- hydroxyethyltriazoledipicolinate complex at 1.51 A resolution.

PDB ID 4baf

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OCA

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