5shf
From Proteopedia
(Difference between revisions)
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| - | == | + | ==CRYSTAL STRUCTURE OF HUMAN PHOSPHODIESTERASE 10 IN COMPLEX WITH c1c(C)nc(c(c1)C)C(=O)Nc4cn2c(cc(n2)c3ccccc3)cc4, micromolar IC50=0.052936== |
<StructureSection load='5shf' size='340' side='right'caption='[[5shf]], [[Resolution|resolution]] 2.28Å' scene=''> | <StructureSection load='5shf' size='340' side='right'caption='[[5shf]], [[Resolution|resolution]] 2.28Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[5shf]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5SHF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5SHF FirstGlance]. <br> | <table><tr><td colspan='2'>[[5shf]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5SHF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5SHF FirstGlance]. <br> | ||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.28Å</td></tr> | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.28Å</td></tr> | ||
| - | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CME:S,S-(2-HYDROXYETHYL)THIOCYSTEINE'>CME</scene>, <scene name='pdbligand=JFG:3,6-dimethyl-N- | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CME:S,S-(2-HYDROXYETHYL)THIOCYSTEINE'>CME</scene>, <scene name='pdbligand=JFG:3,6-dimethyl-~{N}-(2-phenylpyrazolo[1,5-a]pyridin-6-yl)pyridine-2-carboxamide'>JFG</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> |
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5shf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5shf OCA], [https://pdbe.org/5shf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5shf RCSB], [https://www.ebi.ac.uk/pdbsum/5shf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5shf ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5shf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5shf OCA], [https://pdbe.org/5shf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5shf RCSB], [https://www.ebi.ac.uk/pdbsum/5shf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5shf ProSAT]</span></td></tr> | ||
</table> | </table> | ||
Current revision
CRYSTAL STRUCTURE OF HUMAN PHOSPHODIESTERASE 10 IN COMPLEX WITH c1c(C)nc(c(c1)C)C(=O)Nc4cn2c(cc(n2)c3ccccc3)cc4, micromolar IC50=0.052936
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