5sk9

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==Crystal Structure of human phosphodiesterase 10 in complex with 2-chloro-5-methoxy-3-methylquinoxaline==
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==CRYSTAL STRUCTURE OF HUMAN PHOSPHODIESTERASE 10 IN COMPLEX WITH COc1cccc2nc(Cl)c(C)nc12, micromolar IC50=7.99191==
<StructureSection load='5sk9' size='340' side='right'caption='[[5sk9]], [[Resolution|resolution]] 2.82&Aring;' scene=''>
<StructureSection load='5sk9' size='340' side='right'caption='[[5sk9]], [[Resolution|resolution]] 2.82&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[5sk9]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5SK9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5SK9 FirstGlance]. <br>
<table><tr><td colspan='2'>[[5sk9]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5SK9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5SK9 FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.82&#8491;</td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.82&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=KD4:2-chloro-5-methoxy-3-methylquinoxaline'>KD4</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=KD4:2-chloranyl-5-methoxy-3-methyl-quinoxaline'>KD4</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5sk9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5sk9 OCA], [https://pdbe.org/5sk9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5sk9 RCSB], [https://www.ebi.ac.uk/pdbsum/5sk9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5sk9 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5sk9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5sk9 OCA], [https://pdbe.org/5sk9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5sk9 RCSB], [https://www.ebi.ac.uk/pdbsum/5sk9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5sk9 ProSAT]</span></td></tr>
</table>
</table>

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CRYSTAL STRUCTURE OF HUMAN PHOSPHODIESTERASE 10 IN COMPLEX WITH COc1cccc2nc(Cl)c(C)nc12, micromolar IC50=7.99191

PDB ID 5sk9

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