6jjx

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 <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6jjx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6jjx OCA], [https://pdbe.org/6jjx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6jjx RCSB], [https://www.ebi.ac.uk/pdbsum/6jjx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6jjx ProSAT]</span></td></tr>
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-== Function ==
-[https://www.uniprot.org/uniprot/KIBRA_MOUSE KIBRA_MOUSE] Probable regulator of the Hippo/SWH (Sav/Wts/Hpo) signaling pathway, a signaling pathway that plays a pivotal role in tumor suppression by restricting proliferation and promoting apoptosis. Along with NF2 can synergistically induce the phosphorylation of LATS1 and LATS2 and can probably function in the regulation of the Hippo/SWH (Sav/Wts/Hpo) signaling pathway. Acts as a transcriptional coactivator of ESR1 which plays an essential role in DYNLL1-mediated ESR1 transactivation. Regulates collagen-stimulated activation of the ERK/MAPK cascade. Modulates directional migration of podocytes. Acts as a substrate for PRKCZ and may be associated with memory performance (By similarity). Regulates collagen-stimulated activation of the ERK/MAPK cascade.<ref>PMID:18190796</ref>
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 == Publication Abstract from PubMed ==