6l65
From Proteopedia
(Difference between revisions)
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6l65 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6l65 OCA], [https://pdbe.org/6l65 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6l65 RCSB], [https://www.ebi.ac.uk/pdbsum/6l65 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6l65 ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6l65 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6l65 OCA], [https://pdbe.org/6l65 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6l65 RCSB], [https://www.ebi.ac.uk/pdbsum/6l65 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6l65 ProSAT]</span></td></tr> | ||
</table> | </table> | ||
| - | == Function == | ||
| - | [https://www.uniprot.org/uniprot/SIR2_HUMAN SIR2_HUMAN] NAD-dependent protein deacetylase, which deacetylates internal lysines on histone and non-histone proteins. Deacetylates 'Lys-40' of alpha-tubulin. Involved in the control of mitotic exit in the cell cycle, probably via its role in the regulation of cytoskeleton. Deacetylates PCK1, opposing proteasomal degradation. Deacetylates 'Lys-310' of RELA.<ref>PMID:12620231</ref> <ref>PMID:12697818</ref> <ref>PMID:21081649</ref> <ref>PMID:21726808</ref> | ||
==See Also== | ==See Also== | ||
*[[Histone deacetylase 3D structures|Histone deacetylase 3D structures]] | *[[Histone deacetylase 3D structures|Histone deacetylase 3D structures]] | ||
| - | == References == | ||
| - | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
Current revision
Sirtuin 2 protein with H3K18 myristoylated peptide
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