6y4s

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (08:29, 17 October 2024) (edit) (undo)
 
Line 3: Line 3:
<StructureSection load='6y4s' size='340' side='right'caption='[[6y4s]], [[Resolution|resolution]] 2.23&Aring;' scene=''>
<StructureSection load='6y4s' size='340' side='right'caption='[[6y4s]], [[Resolution|resolution]] 2.23&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[6y4s]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6Y4S OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6Y4S FirstGlance]. <br>
+
<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6Y4S OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6Y4S FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.23&#8491;</td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.23&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PGE:TRIETHYLENE+GLYCOL'>PGE</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PGE:TRIETHYLENE+GLYCOL'>PGE</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6y4s FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6y4s OCA], [https://pdbe.org/6y4s PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6y4s RCSB], [https://www.ebi.ac.uk/pdbsum/6y4s PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6y4s ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6y4s FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6y4s OCA], [https://pdbe.org/6y4s PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6y4s RCSB], [https://www.ebi.ac.uk/pdbsum/6y4s PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6y4s ProSAT]</span></td></tr>
</table>
</table>
-
== Function ==
 
-
[https://www.uniprot.org/uniprot/KLK7_HUMAN KLK7_HUMAN] May catalyze the degradation of intercellular cohesive structures in the cornified layer of the skin in the continuous shedding of cells from the skin surface. Specific for amino acid residues with aromatic side chains in the P1 position. SCCE cleaves insulin B chain at '6-Leu-|-Cys-7', '16-Tyr-|-Leu-17', '25-Phe-|-Tyr-26' and '26-Tyr-|-Thr-27'. Could play a role in the activation of precursors to inflammatory cytokines.
 
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
Line 26: Line 24:
__TOC__
__TOC__
</StructureSection>
</StructureSection>
-
[[Category: Homo sapiens]]
 
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Hanke S]]
[[Category: Hanke S]]
[[Category: Strater N]]
[[Category: Strater N]]

Current revision

Human kallikrein-related peptidase 7 (KLK7) in the unliganded state

PDB ID 6y4s

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/6y4s"
Personal tools