7bhe
From Proteopedia
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7bhe FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7bhe OCA], [https://pdbe.org/7bhe PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7bhe RCSB], [https://www.ebi.ac.uk/pdbsum/7bhe PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7bhe ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7bhe FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7bhe OCA], [https://pdbe.org/7bhe PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7bhe RCSB], [https://www.ebi.ac.uk/pdbsum/7bhe PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7bhe ProSAT]</span></td></tr> | ||
</table> | </table> | ||
| - | == Disease == | ||
| - | [https://www.uniprot.org/uniprot/ERBB3_HUMAN ERBB3_HUMAN] Defects in ERBB3 are the cause of lethal congenital contracture syndrome type 2 (LCCS2) [MIM:[https://omim.org/entry/607598 607598]; also called Israeli Bedouin multiple contracture syndrome type A. LCCS2 is an autosomal recessive neurogenic form of a neonatally lethal arthrogryposis that is associated with atrophy of the anterior horn of the spinal cord. The LCCS2 syndrome is characterized by multiple joint contractures, anterior horn atrophy in the spinal cord, and a unique feature of a markedly distended urinary bladder. The phenotype suggests a spinal cord neuropathic etiology.<ref>PMID:17701904</ref> | ||
| - | == Function == | ||
| - | [https://www.uniprot.org/uniprot/ERBB3_HUMAN ERBB3_HUMAN] Binds and is activated by neuregulins and NTAK.<ref>PMID:15358134</ref> | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
Current revision
DARPin_D5/Her3 domain 4 complex, monoclinic crystals
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