8ax6
From Proteopedia
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8ax6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8ax6 OCA], [https://pdbe.org/8ax6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8ax6 RCSB], [https://www.ebi.ac.uk/pdbsum/8ax6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8ax6 ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8ax6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8ax6 OCA], [https://pdbe.org/8ax6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8ax6 RCSB], [https://www.ebi.ac.uk/pdbsum/8ax6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8ax6 ProSAT]</span></td></tr> | ||
</table> | </table> | ||
| - | == Function == | ||
| - | [https://www.uniprot.org/uniprot/MALE_ECOLI MALE_ECOLI] Involved in the high-affinity maltose membrane transport system MalEFGK. Initial receptor for the active transport of and chemotaxis toward maltooligosaccharides.[https://www.uniprot.org/uniprot/RAMP1_HUMAN RAMP1_HUMAN] Transports the calcitonin gene-related peptide type 1 receptor (CALCRL) to the plasma membrane. Acts as a receptor for calcitonin-gene-related peptide (CGRP) together with CALCRL.<ref>PMID:9620797</ref> [https://www.uniprot.org/uniprot/CALRL_HUMAN CALRL_HUMAN] Receptor for calcitonin-gene-related peptide (CGRP) together with RAMP1 and receptor for adrenomedullin together with RAMP3 (By similarity). Receptor for adrenomedullin together with RAMP2. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase.<ref>PMID:22102369</ref> | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
Current revision
Crystal structure of a CGRP receptor ectodomain heterodimer bound to macrocyclic inhibitor HTL0029882
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