2uvk

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Current revision (07:58, 23 October 2024) (edit) (undo)
 
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<StructureSection load='2uvk' size='340' side='right'caption='[[2uvk]], [[Resolution|resolution]] 1.50&Aring;' scene=''>
<StructureSection load='2uvk' size='340' side='right'caption='[[2uvk]], [[Resolution|resolution]] 1.50&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2uvk]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Ecobb Ecobb]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2UVK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2UVK FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2uvk]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_BL21 Escherichia coli BL21]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2UVK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2UVK FirstGlance]. <br>
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</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.5&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2uvk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2uvk OCA], [https://pdbe.org/2uvk PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2uvk RCSB], [https://www.ebi.ac.uk/pdbsum/2uvk PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2uvk ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2uvk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2uvk OCA], [https://pdbe.org/2uvk PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2uvk RCSB], [https://www.ebi.ac.uk/pdbsum/2uvk PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2uvk ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[https://www.uniprot.org/uniprot/NANM_ECOLI NANM_ECOLI]] Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses.<ref>PMID:18063573</ref>
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[https://www.uniprot.org/uniprot/NANM_ECOLI NANM_ECOLI] Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses.<ref>PMID:18063573</ref>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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<jmolCheckbox>
<jmolCheckbox>
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/uv/2uvk_consurf.spt"</scriptWhenChecked>
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/uv/2uvk_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
</jmolCheckbox>
</jmolCheckbox>
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Ecobb]]
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[[Category: Escherichia coli BL21]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Muller, A]]
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[[Category: Muller A]]
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[[Category: Severi, E]]
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[[Category: Severi E]]
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[[Category: Thomas, G H]]
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[[Category: Thomas GH]]
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[[Category: Wilson, K S]]
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[[Category: Wilson KS]]
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[[Category: Beta-propeller]]
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[[Category: Hypothetical protein]]
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[[Category: Kelch repeat]]
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[[Category: Sialic acid metabolism]]
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[[Category: Unknown function]]
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Current revision

Structure of YjhT

PDB ID 2uvk

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