5v54

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (09:29, 23 October 2024) (edit) (undo)
 
Line 3: Line 3:
<StructureSection load='5v54' size='340' side='right'caption='[[5v54]], [[Resolution|resolution]] 3.90&Aring;' scene=''>
<StructureSection load='5v54' size='340' side='right'caption='[[5v54]], [[Resolution|resolution]] 3.90&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[5v54]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5V54 OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=5V54 FirstGlance]. <br>
+
<table><tr><td colspan='2'>[[5v54]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Spodoptera_frugiperda Spodoptera frugiperda]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5V54 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5V54 FirstGlance]. <br>
-
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=89F:1-methyl-4-[(5~{S})-3-methylsulfanyl-5,6-dihydrobenzo[b][1]benzothiepin-5-yl]piperazine'>89F</scene></td></tr>
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.9&#8491;</td></tr>
-
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=5v54 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5v54 OCA], [http://pdbe.org/5v54 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5v54 RCSB], [http://www.ebi.ac.uk/pdbsum/5v54 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5v54 ProSAT]</span></td></tr>
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=89F:1-methyl-4-[(5~{S})-3-methylsulfanyl-5,6-dihydrobenzo[b][1]benzothiepin-5-yl]piperazine'>89F</scene></td></tr>
 +
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5v54 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5v54 OCA], [https://pdbe.org/5v54 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5v54 RCSB], [https://www.ebi.ac.uk/pdbsum/5v54 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5v54 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
-
[[http://www.uniprot.org/uniprot/5HT1B_HUMAN 5HT1B_HUMAN]] This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that inhibit adenylate cyclase activity.
+
[https://www.uniprot.org/uniprot/5HT1B_HUMAN 5HT1B_HUMAN] This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that inhibit adenylate cyclase activity.
==See Also==
==See Also==
Line 14: Line 15:
__TOC__
__TOC__
</StructureSection>
</StructureSection>
 +
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
-
[[Category: Caffrey, M]]
+
[[Category: Spodoptera frugiperda]]
-
[[Category: Cai, X]]
+
[[Category: Caffrey M]]
-
[[Category: Dai, A]]
+
[[Category: Cai X]]
-
[[Category: Huang, C Y]]
+
[[Category: Dai A]]
-
[[Category: Jiang, Y]]
+
[[Category: Huang CY]]
-
[[Category: Liu, B]]
+
[[Category: Jiang Y]]
-
[[Category: Liu, P]]
+
[[Category: Liu B]]
-
[[Category: Melcher, K]]
+
[[Category: Liu P]]
-
[[Category: Waal, P de]]
+
[[Category: Melcher K]]
-
[[Category: Wang, M T]]
+
[[Category: Wang MT]]
-
[[Category: Wang, M W]]
+
[[Category: Wang MW]]
-
[[Category: Xu, H E]]
+
[[Category: Xu HE]]
-
[[Category: Xu, Y]]
+
[[Category: Xu Y]]
-
[[Category: Yang, D]]
+
[[Category: Yang D]]
-
[[Category: Yin, W C]]
+
[[Category: Yin WC]]
-
[[Category: Yin, Y]]
+
[[Category: Yin Y]]
-
[[Category: Zhou, X E]]
+
[[Category: Zhou XE]]
-
[[Category: 5-hydroxytryptamine]]
+
[[Category: De Waal P]]
-
[[Category: Electron transport]]
+
-
[[Category: Gpcr antagonist]]
+
-
[[Category: Ob1]]
+

Current revision

Crystal structure of 5-HT1B receptor in complex with methiothepin

PDB ID 5v54

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Personal tools