6gt3

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<StructureSection load='6gt3' size='340' side='right'caption='[[6gt3]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
<StructureSection load='6gt3' size='340' side='right'caption='[[6gt3]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[6gt3]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6GT3 OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=6GT3 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[6gt3]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli] and [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6GT3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6GT3 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CLR:CHOLESTEROL'>CLR</scene>, <scene name='pdbligand=F9Q:6-(2-chloranyl-6-methyl-pyridin-4-yl)-5-(4-fluorophenyl)-1,2,4-triazin-3-amine'>F9Q</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=OLA:OLEIC+ACID'>OLA</scene>, <scene name='pdbligand=OLC:(2R)-2,3-DIHYDROXYPROPYL+(9Z)-OCTADEC-9-ENOATE'>OLC</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">ADORA2A, ADORA2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 "Bacillus coli" Migula 1895])</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CLR:CHOLESTEROL'>CLR</scene>, <scene name='pdbligand=F9Q:6-(2-chloranyl-6-methyl-pyridin-4-yl)-5-(4-fluorophenyl)-1,2,4-triazin-3-amine'>F9Q</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=OLA:OLEIC+ACID'>OLA</scene>, <scene name='pdbligand=OLC:(2R)-2,3-DIHYDROXYPROPYL+(9Z)-OCTADEC-9-ENOATE'>OLC</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=6gt3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6gt3 OCA], [http://pdbe.org/6gt3 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6gt3 RCSB], [http://www.ebi.ac.uk/pdbsum/6gt3 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6gt3 ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6gt3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6gt3 OCA], [https://pdbe.org/6gt3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6gt3 RCSB], [https://www.ebi.ac.uk/pdbsum/6gt3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6gt3 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/AA2AR_HUMAN AA2AR_HUMAN]] Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase.
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[https://www.uniprot.org/uniprot/AA2AR_HUMAN AA2AR_HUMAN] Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase.[https://www.uniprot.org/uniprot/C562_ECOLX C562_ECOLX] Electron-transport protein of unknown function.
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==See Also==
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*[[Adenosine A2A receptor 3D structures|Adenosine A2A receptor 3D structures]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Bacillus coli migula 1895]]
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[[Category: Escherichia coli]]
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[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Andrews, S P]]
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[[Category: Andrews SP]]
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[[Category: Borodovsky, A]]
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[[Category: Borodovsky A]]
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[[Category: Brown, G A]]
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[[Category: Brown GA]]
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[[Category: Cheng, R K.Y]]
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[[Category: Cheng RKY]]
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[[Category: Clarke, J D]]
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[[Category: Clarke JD]]
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[[Category: Congreve, M]]
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[[Category: Congreve M]]
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[[Category: Deng, N]]
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[[Category: Deng N]]
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[[Category: Dore, A S]]
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[[Category: Dore AS]]
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[[Category: Goodwin, K]]
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[[Category: Goodwin K]]
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[[Category: Goodwin, R]]
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[[Category: Goodwin R]]
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[[Category: Hay, C]]
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[[Category: Hay C]]
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[[Category: Lyne, P]]
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[[Category: Lyne P]]
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[[Category: Marshall, F H]]
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[[Category: Marshall FH]]
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[[Category: Mason, J S]]
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[[Category: Mason JS]]
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[[Category: Reimer, C]]
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[[Category: Reimer C]]
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[[Category: Sachsenmeier, K]]
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[[Category: Sachsenmeier K]]
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[[Category: Shaw, J]]
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[[Category: Shaw J]]
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[[Category: Stephen, T L]]
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[[Category: Stephen TL]]
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[[Category: Strittmatter, N]]
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[[Category: Strittmatter N]]
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[[Category: Wang, Y]]
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[[Category: Wang Y]]
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[[Category: Weir, M P]]
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[[Category: Weir MP]]
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[[Category: Woessner, R]]
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[[Category: Woessner R]]
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[[Category: Ye, M]]
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[[Category: Ye M]]
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[[Category: Gpcr]]
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[[Category: Membrane protein]]
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[[Category: Signalling protein]]
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Current revision

Crystal Structure of the A2A-StaR2-bRIL562 in complex with AZD4635 at 2.0A resolution

PDB ID 6gt3

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