6jau

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Current revision (10:05, 23 October 2024) (edit) (undo)
 
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<StructureSection load='6jau' size='340' side='right'caption='[[6jau]], [[Resolution|resolution]] 1.91&Aring;' scene=''>
<StructureSection load='6jau' size='340' side='right'caption='[[6jau]], [[Resolution|resolution]] 1.91&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[6jau]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Pseae Pseae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6JAU OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=6JAU FirstGlance]. <br>
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<table><tr><td colspan='2'>[[6jau]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_aeruginosa_PAO1 Pseudomonas aeruginosa PAO1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6JAU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6JAU FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=P6G:HEXAETHYLENE+GLYCOL'>P6G</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.905&#8491;</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">mucB, algN, PA0764 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=208964 PSEAE]), mucA, PA0763 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=208964 PSEAE])</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=P6G:HEXAETHYLENE+GLYCOL'>P6G</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=6jau FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6jau OCA], [http://pdbe.org/6jau PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6jau RCSB], [http://www.ebi.ac.uk/pdbsum/6jau PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6jau ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6jau FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6jau OCA], [https://pdbe.org/6jau PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6jau RCSB], [https://www.ebi.ac.uk/pdbsum/6jau PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6jau ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/MUCB_PSEAE MUCB_PSEAE]] Negative regulator of the sigma factor AlgU. Plays a role in the differentiation of P.aeruginosa into the alginate-producing form. Inactivation of mucB causes conversion to mucoidy. [[http://www.uniprot.org/uniprot/MUCA_PSEAE MUCA_PSEAE]] Negative regulator of the sigma factor AlgU. Plays a role in the differentiation of P.aeruginosa into the alginate-producing form. Inactivation of mucA causes a switch from the non-mucoid to mucoid state resulting in constitutive expression of alginate biosynthetic genes.
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[https://www.uniprot.org/uniprot/MUCB_PSEAE MUCB_PSEAE] Negative regulator of the sigma factor AlgU. Plays a role in the differentiation of P.aeruginosa into the alginate-producing form. Inactivation of mucB causes conversion to mucoidy.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Pseae]]
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[[Category: Pseudomonas aeruginosa PAO1]]
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[[Category: Bao, R]]
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[[Category: Bao R]]
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[[Category: He, L H]]
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[[Category: He LH]]
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[[Category: Huang, Q]]
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[[Category: Huang Q]]
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[[Category: Li, C C]]
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[[Category: Li CC]]
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[[Category: Li, T]]
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[[Category: Li T]]
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[[Category: Liu, L]]
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[[Category: Liu L]]
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[[Category: Mu, X Y]]
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[[Category: Mu XY]]
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[[Category: Peng, C T]]
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[[Category: Peng CT]]
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[[Category: Qin, X F]]
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[[Category: Qin XF]]
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[[Category: Shen, Y L]]
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[[Category: Shen YL]]
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[[Category: Song, Y J]]
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[[Category: Song YJ]]
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[[Category: Xiao, Q J]]
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[[Category: Xiao QJ]]
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[[Category: Yang, J]]
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[[Category: Yang J]]
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[[Category: Zhao, C]]
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[[Category: Zhao C]]
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[[Category: Zhao, N l]]
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[[Category: Zhao Nl]]
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[[Category: Zhu, Y B]]
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[[Category: Zhu YB]]
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[[Category: Alginate]]
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[[Category: Lp]]
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[[Category: Muca/mucb]]
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[[Category: Protein binding]]
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[[Category: Regulated intramembrane proteolysis]]
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Current revision

The complex structure of Pseudomonas aeruginosa MucA/MucB.

PDB ID 6jau

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Proteopedia Page Contributors and Editors (what is this?)

OCA

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