6nbn
From Proteopedia
(Difference between revisions)
| Line 4: | Line 4: | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[6nbn]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Aedes_aegypti Aedes aegypti]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6NBN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6NBN FirstGlance]. <br> | <table><tr><td colspan='2'>[[6nbn]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Aedes_aegypti Aedes aegypti]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6NBN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6NBN FirstGlance]. <br> | ||
| - | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACD:ARACHIDONIC+ACID'>ACD</scene></td></tr> | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR, 30 models</td></tr> |
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACD:ARACHIDONIC+ACID'>ACD</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6nbn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6nbn OCA], [https://pdbe.org/6nbn PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6nbn RCSB], [https://www.ebi.ac.uk/pdbsum/6nbn PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6nbn ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6nbn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6nbn OCA], [https://pdbe.org/6nbn PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6nbn RCSB], [https://www.ebi.ac.uk/pdbsum/6nbn PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6nbn ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
| - | [https://www.uniprot.org/uniprot/ | + | [https://www.uniprot.org/uniprot/OBP22_AEDAE OBP22_AEDAE] Involved in modulation of blood-feeding behavior and capacity in female mosquitoes (PubMed:22479185, PubMed:34634943). Required for normal oviposition (PubMed:34634943). Required for normal fecundity and fertility of female and male mosquitoes (PubMed:34634943). Required for normal expression of VGA1 gene, which encodes the egg yolk protein vitellogenin-A1 (PubMed:34634943). Involved in regulation of spermatozoa development (PubMed:34634943). Required for normal female longevity when mosquitoes are maintained on regular sugar meal (PubMed:34634943). Binds long chain fatty acids (PubMed:32094450).<ref>PMID:22479185</ref> <ref>PMID:32094450</ref> <ref>PMID:34634943</ref> (Microbial infection) Facilitates shedding of dengue virus type 2 particles into mosquito saliva (PubMed:34634943). Does not affect dengue virus type 2 replication or infection prevalence in midgut and salivary glands at 14 days after blood feeding (PubMed:34634943).<ref>PMID:34634943</ref> (Microbial infection) Facilitates shedding of Zika virus particles into mosquito saliva (PubMed:34634943). Does not affect Zika virus replication or infection prevalence in midgut and salivary glands at 14 days after blood feeding (PubMed:34634943).<ref>PMID:34634943</ref> |
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
Current revision
Structure of Aedes aegypti OBP22 in the complex with arachidonic acid
| |||||||||||
