6pol
From Proteopedia
(Difference between revisions)
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<StructureSection load='6pol' size='340' side='right'caption='[[6pol]], [[Resolution|resolution]] 1.80Å' scene=''> | <StructureSection load='6pol' size='340' side='right'caption='[[6pol]], [[Resolution|resolution]] 1.80Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'> | + | <table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6POL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6POL FirstGlance]. <br> |
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8Å</td></tr> | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8Å</td></tr> | ||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=NO3:NITRATE+ION'>NO3</scene></td></tr> | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=NO3:NITRATE+ION'>NO3</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6pol FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6pol OCA], [https://pdbe.org/6pol PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6pol RCSB], [https://www.ebi.ac.uk/pdbsum/6pol PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6pol ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6pol FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6pol OCA], [https://pdbe.org/6pol PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6pol RCSB], [https://www.ebi.ac.uk/pdbsum/6pol PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6pol ProSAT]</span></td></tr> | ||
</table> | </table> | ||
| - | == Disease == | ||
| - | [https://www.uniprot.org/uniprot/ROBO3_HUMAN ROBO3_HUMAN] Horizontal gaze palsy with progressive scoliosis. The disease is caused by variants affecting the gene represented in this entry. | ||
| - | == Function == | ||
| - | [https://www.uniprot.org/uniprot/ROBO3_HUMAN ROBO3_HUMAN] Thought to be involved during neural development in axonal navigation at the ventral midline of the neural tube (By similarity). In spinal cord development plays a role in guiding commissural axons probably by preventing premature sensitivity to Slit proteins thus inhibiting Slit signaling through ROBO1 (By similarity). Required for hindbrain axon midline crossing (PubMed:15105459).[UniProtKB:Q9Z2I4]<ref>PMID:15105459</ref> | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: Homo sapiens]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: Ozkan E]] | [[Category: Ozkan E]] | ||
[[Category: Pak JS]] | [[Category: Pak JS]] | ||
[[Category: Wang J]] | [[Category: Wang J]] | ||
Current revision
Crystal structure of the human NELL1 EGF1-3-Robo3 FN1 complex
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