3rjr

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Current revision (09:38, 30 October 2024) (edit) (undo)
 
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<StructureSection load='3rjr' size='340' side='right'caption='[[3rjr]], [[Resolution|resolution]] 3.05&Aring;' scene=''>
<StructureSection load='3rjr' size='340' side='right'caption='[[3rjr]], [[Resolution|resolution]] 3.05&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3rjr]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Pig Pig]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3RJR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3RJR FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3rjr]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Sus_scrofa Sus scrofa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3RJR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3RJR FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.05&#8491;</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">TGFB1 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9823 PIG])</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3rjr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3rjr OCA], [https://pdbe.org/3rjr PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3rjr RCSB], [https://www.ebi.ac.uk/pdbsum/3rjr PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3rjr ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3rjr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3rjr OCA], [https://pdbe.org/3rjr PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3rjr RCSB], [https://www.ebi.ac.uk/pdbsum/3rjr PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3rjr ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[https://www.uniprot.org/uniprot/TGFB1_PIG TGFB1_PIG]] Multifunctional protein that controls proliferation, differentiation and other functions in many cell types. Many cells synthesize TGFB1 and have specific receptors for it. It positively and negatively regulates many other growth factors. It plays an important role in bone remodeling as it is a potent stimulator of osteoblastic bone formation, causing chemotaxis, proliferation and differentiation in committed osteoblasts (By similarity).
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[https://www.uniprot.org/uniprot/TGFB1_PIG TGFB1_PIG] Multifunctional protein that controls proliferation, differentiation and other functions in many cell types. Many cells synthesize TGFB1 and have specific receptors for it. It positively and negatively regulates many other growth factors. It plays an important role in bone remodeling as it is a potent stimulator of osteoblastic bone formation, causing chemotaxis, proliferation and differentiation in committed osteoblasts (By similarity).
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Pig]]
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[[Category: Sus scrofa]]
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[[Category: Shi, M L]]
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[[Category: Shi ML]]
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[[Category: Springer, T A]]
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[[Category: Springer TA]]
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[[Category: Zhu, J H]]
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[[Category: Zhu JH]]
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[[Category: Activation]]
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[[Category: Cytokine]]
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[[Category: Integrin]]
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[[Category: Tgf beta]]
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Current revision

Crystal Structure of pro-TGF beta 1

PDB ID 3rjr

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Proteopedia Page Contributors and Editors (what is this?)

OCA

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