5vb9

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Current revision (10:54, 30 October 2024) (edit) (undo)
 
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<StructureSection load='5vb9' size='340' side='right'caption='[[5vb9]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
<StructureSection load='5vb9' size='340' side='right'caption='[[5vb9]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[5vb9]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5VB9 OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=5VB9 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[5vb9]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5VB9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5VB9 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.7&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=5vb9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5vb9 OCA], [http://pdbe.org/5vb9 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5vb9 RCSB], [http://www.ebi.ac.uk/pdbsum/5vb9 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5vb9 ProSAT]</span></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5vb9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5vb9 OCA], [https://pdbe.org/5vb9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5vb9 RCSB], [https://www.ebi.ac.uk/pdbsum/5vb9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5vb9 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/IL17_HUMAN IL17_HUMAN]] Induces stromal cells to produce proinflammatory and hematopoietic cytokines. Enhances the surface expression of ICAM1/intracellular adhesion molecule 1 in fibroblasts.
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[https://www.uniprot.org/uniprot/IL17_HUMAN IL17_HUMAN] Induces stromal cells to produce proinflammatory and hematopoietic cytokines. Enhances the surface expression of ICAM1/intracellular adhesion molecule 1 in fibroblasts.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Afshar, S]]
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[[Category: Synthetic construct]]
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[[Category: Antonysamy, S]]
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[[Category: Afshar S]]
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[[Category: Benach, J]]
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[[Category: Antonysamy S]]
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[[Category: Bina, H]]
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[[Category: Benach J]]
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[[Category: Broughton, H]]
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[[Category: Bina H]]
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[[Category: Chalmers, M]]
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[[Category: Broughton H]]
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[[Category: Dodge, J]]
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[[Category: Chalmers M]]
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[[Category: Espada, A]]
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[[Category: Dodge J]]
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[[Category: Groshong, C]]
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[[Category: Espada A]]
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[[Category: Jones, S]]
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[[Category: Groshong C]]
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[[Category: Lu, F]]
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[[Category: Jones S]]
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[[Category: Manglicmot, D]]
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[[Category: Lu F]]
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[[Category: Russell, M]]
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[[Category: Manglicmot D]]
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[[Category: Ting, J P]]
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[[Category: Russell M]]
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[[Category: Wasserman, S R]]
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[[Category: Ting JP]]
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[[Category: Woodman, M]]
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[[Category: Wasserman SR]]
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[[Category: Zhang, A]]
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[[Category: Woodman M]]
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[[Category: Zhang, F]]
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[[Category: Zhang A]]
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[[Category: Il17]]
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[[Category: Zhang F]]
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[[Category: Immune system - inhibitor complex]]
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[[Category: Inhibitor]]
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Current revision

IL-17A in complex with peptide

PDB ID 5vb9

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Proteopedia Page Contributors and Editors (what is this?)

OCA

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