5xsy

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Current revision (10:57, 30 October 2024) (edit) (undo)
 
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<SX load='5xsy' size='340' side='right' viewer='molstar' caption='[[5xsy]], [[Resolution|resolution]] 4.00&Aring;' scene=''>
<SX load='5xsy' size='340' side='right' viewer='molstar' caption='[[5xsy]], [[Resolution|resolution]] 4.00&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[5xsy]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Electrophorus_electricus Electrophorus electricus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5XSY OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=5XSY FirstGlance]. <br>
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<table><tr><td colspan='2'>[[5xsy]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Electrophorus_electricus Electrophorus electricus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5XSY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5XSY FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 4&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=5xsy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5xsy OCA], [http://pdbe.org/5xsy PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5xsy RCSB], [http://www.ebi.ac.uk/pdbsum/5xsy PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5xsy ProSAT]</span></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5xsy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5xsy OCA], [https://pdbe.org/5xsy PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5xsy RCSB], [https://www.ebi.ac.uk/pdbsum/5xsy PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5xsy ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/SCNA_ELEEL SCNA_ELEEL]] Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient.<ref>PMID:2442385</ref>
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[https://www.uniprot.org/uniprot/SCNA_ELEEL SCNA_ELEEL] Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient.<ref>PMID:2442385</ref>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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[[Category: Electrophorus electricus]]
[[Category: Electrophorus electricus]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Wu, J P]]
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[[Category: Wu JP]]
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[[Category: Yan, N]]
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[[Category: Yan N]]
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[[Category: Yan, Z]]
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[[Category: Yan Z]]
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[[Category: Zhou, Q]]
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[[Category: Zhou Q]]
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[[Category: Membrane protein]]
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[[Category: Voltage gated sodium channel]]
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Current revision

Structure of the Nav1.4-beta1 complex from electric eel

5xsy, resolution 4.00Å

Proteopedia Page Contributors and Editors (what is this?)

OCA

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