6nr2

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Current revision (11:14, 30 October 2024) (edit) (undo)
 
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<SX load='6nr2' size='340' side='right' viewer='molstar' caption='[[6nr2]], [[Resolution|resolution]] 4.00&Aring;' scene=''>
<SX load='6nr2' size='340' side='right' viewer='molstar' caption='[[6nr2]], [[Resolution|resolution]] 4.00&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[6nr2]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Collared_flycatcher Collared flycatcher]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6NR2 OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=6NR2 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[6nr2]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Ficedula_albicollis Ficedula albicollis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6NR2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6NR2 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=KXP:(2S)-1-{[(R)-hydroxy{[(1R,2R,3S,4R,5R,6S)-2,3,6-trihydroxy-4,5-bis(phosphonooxy)cyclohexyl]oxy}phosphoryl]oxy}-3-(octadecanoyloxy)propan-2-yl+icosa-5,8,11,14-tetraenoate'>KXP</scene>, <scene name='pdbligand=KXS:(1R,2S,5R)-N-(4-methoxyphenyl)-5-methyl-2-(propan-2-yl)cyclohexane-1-carboxamide'>KXS</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 4&#8491;</td></tr>
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<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=UNK:UNKNOWN'>UNK</scene></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=KXP:[(2~{S})-1-octadecanoyloxy-3-[oxidanyl-[(1~{R},2~{R},3~{S},4~{R},5~{R},6~{S})-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phosphoryl]oxy-propan-2-yl]+icosa-5,8,11,14-tetraenoate'>KXP</scene>, <scene name='pdbligand=KXS:(1R,2S,5R)-N-(4-methoxyphenyl)-5-methyl-2-(propan-2-yl)cyclohexane-1-carboxamide'>KXS</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">TRPM8 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=59894 Collared flycatcher])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6nr2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6nr2 OCA], [https://pdbe.org/6nr2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6nr2 RCSB], [https://www.ebi.ac.uk/pdbsum/6nr2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6nr2 ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=6nr2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6nr2 OCA], [http://pdbe.org/6nr2 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6nr2 RCSB], [http://www.ebi.ac.uk/pdbsum/6nr2 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6nr2 ProSAT]</span></td></tr>
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</table>
</table>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
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__TOC__
__TOC__
</SX>
</SX>
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[[Category: Collared flycatcher]]
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[[Category: Ficedula albicollis]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Borgnia, M J]]
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[[Category: Borgnia MJ]]
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[[Category: Hsu, A L]]
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[[Category: Hsu AL]]
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[[Category: Le, S C]]
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[[Category: Le SC]]
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[[Category: Lee, S Y]]
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[[Category: Lee S-Y]]
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[[Category: Yang, H]]
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[[Category: Yang H]]
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[[Category: Yin, Y]]
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[[Category: Yin Y]]
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[[Category: Calcium-permeable ion channel]]
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[[Category: Cold sensing]]
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[[Category: Cooling agent]]
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[[Category: Icilin]]
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[[Category: Ion channel]]
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[[Category: Lipid sensing]]
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[[Category: Membrane protein]]
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[[Category: Menthol]]
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[[Category: Transport protein]]
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[[Category: Trp channel]]
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[[Category: Trpm channel]]
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[[Category: Trpm8 channel]]
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[[Category: Ws-12]]
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Current revision

Cryo-EM structure of the TRPM8 ion channel in complex with the menthol analog WS-12 and PI(4,5)P2

6nr2, resolution 4.00Å

Proteopedia Page Contributors and Editors (what is this?)

OCA

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