6vbi
From Proteopedia
(Difference between revisions)
| Line 3: | Line 3: | ||
<StructureSection load='6vbi' size='340' side='right'caption='[[6vbi]], [[Resolution|resolution]] 2.30Å' scene=''> | <StructureSection load='6vbi' size='340' side='right'caption='[[6vbi]], [[Resolution|resolution]] 2.30Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'> | + | <table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6VBI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6VBI FirstGlance]. <br> |
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3000076Å</td></tr> | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3000076Å</td></tr> | ||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FZA:(13bS)-4,9-dimethoxy-14-methyl-8,13,13b,14-tetrahydroindolo[2,3 3,4]pyrido[2,1-b]quinazolin-5(7H)-one'>FZA</scene></td></tr> | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FZA:(13bS)-4,9-dimethoxy-14-methyl-8,13,13b,14-tetrahydroindolo[2,3 3,4]pyrido[2,1-b]quinazolin-5(7H)-one'>FZA</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6vbi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6vbi OCA], [https://pdbe.org/6vbi PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6vbi RCSB], [https://www.ebi.ac.uk/pdbsum/6vbi PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6vbi ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6vbi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6vbi OCA], [https://pdbe.org/6vbi PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6vbi RCSB], [https://www.ebi.ac.uk/pdbsum/6vbi PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6vbi ProSAT]</span></td></tr> | ||
</table> | </table> | ||
| - | == Function == | ||
| - | [https://www.uniprot.org/uniprot/PDE5A_HUMAN PDE5A_HUMAN] Plays a role in signal transduction by regulating the intracellular concentration of cyclic nucleotides. This phosphodiesterase catalyzes the specific hydrolysis of cGMP to 5'-GMP. | ||
==See Also== | ==See Also== | ||
| Line 15: | Line 13: | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: Homo sapiens]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: Ke H]] | [[Category: Ke H]] | ||
[[Category: Luo HB]] | [[Category: Luo HB]] | ||
Current revision
crystal structure of PDE5 in complex with a non-competitive inhibitor
| |||||||||||
